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anosmia

 

Definition

The term anosmia means lack of the sense of smell. It may also refer to a decreased sense of smell. Ageusia, a companion word, refers to a lack of taste sensation. Patients who actually have anosmia may complain wrongly of ageusia, although they retain the ability to distinguish salt, sweet, sour, and bitter—humans' only taste sensations.

Description

Of the five senses, smell ranks fourth in importance for humans, although it is much more pronounced in other animals. Bloodhounds, for example, can smell an odor a thousand times weaker than humans. Taste, considered the fifth sense, is mostly the smell of food in the mouth. The sense of smell originates from the first cranial nerves (the olfactory nerves), which sit at the base of the brain's frontal lobes, right behind the eyes and above the nose. Inhaled airborne chemicals stimulate these nerves.

There are other aberrations of smell beside a decrease. Smells can be distorted, intensified, or hallucinated. These changes usually indicate a malfunction of the brain.

— J. Ricker Polsdorfer, MD



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Dictionary: an·os·mi·a   (ăn-ŏz'mē-ə) pronunciation
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n.
Loss of the sense of smell.

[New Latin : Greek an-, without; see a-1 + Greek osmē, odor.]

anosmic an·os'mic adj.

Wordsmith Words: anosmia
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(an-OZ-mee-uh, -OS-)

noun
Absence or loss of the sense of smell.

Etymology
New Latin, from Greek an- + osm(e) smell (akin to ozein to smell) + -ia.

Usage
"Lack of smell, or anosmia, may result from a host of ills, from viruses to polyps to diseases like Parkinson's or Alzheimer's." — Joseph V. Amodio, Mood Makers, Good Housekeeping, Nov 1998.


Definition

The term anosmia means lack of the sense of smell. It may also refer to a decreased sense of smell. Ageusia, a companion word, refers to a lack of taste sensation. Patients who actually have anosmia may complain wrongly of ageusia, although they retain the ability to distinguish salt, sweet, sour, and bitter—humans' only taste sensations.

Description

Of the five senses, smell ranks fourth in importance for humans, although it is much more pronounced in other animals. Bloodhounds, for example, can smell an odor that is a thousand times weaker than one perceptible by humans. Taste, considered the fifth sense, is mostly the smell of food in the mouth. The sense of smell originates from the first cranial nerves (the olfactory nerves), which sit at the base of the brain's frontal lobes, right behind the eyes and above the nose. Inhaled airborne chemicals stimulate these nerves.

There are other aberrations of smell beside a decrease. Smells can be distorted, intensified, or hallucinated. These changes usually indicate a malfunction of the brain.

Causes and symptoms

The most common cause of anosmia is nasal occlusion caused by rhinitis (inflammation of the nasal membranes). If no air gets to the olfactory nerves, smell will not happen. In turn, rhinitis and nasal polyps (growths on nasal membranes) are caused by irritants such as allergens, infections, cigarette smoke, and other air pollutants. Tumors such as nasal polyps can also block the nasal passages and the olfactory nerves and cause anosmia. Head injury or, rarely, certain viral infections can damage or destroy the olfactory nerves.

Diagnosis

It is difficult to measure a loss of smell, and no one complains of loss of smell in just one nostril. So a physician usually begins by testing each nostril separately with a common, non-irritating odor such as perfume, lemon, vanilla, or coffee. Polyps and rhinitis are obvious causal agents a physician looks for. Imaging studies of the head may be necessary in order to detect brain injury, sinus infection, or tumor.

Treatment

Cessation of smoking is one step. Many smokers who quit discover new tastes so enthusiastically that they immediately gain weight. Attention to reducing exposure to other nasal irritants and treatment of respiratory allergies or chronic upper respiratory infections will be beneficial. Corticosteroids are particularly helpful.

Alternative treatment

Finding and treating the cause of the loss of smell is the first approach in naturopathic medicine. If rhinitis is the cause, treating acute rhinitis with herbal mast cell stabilizers and herbal decongestants can offer some relief as the body heals. If chronic rhinitis is present, this is often related to an environmental irritant or to food allergies. Removal of the causative factors is the first step to healing. Nasal steams with essential oils offer relief of the blockage and tonification of the membranes. Blockages can sometimes be resolved through naso-specific therapy—a way of realigning the nasal cavities. Polyp blockage can be addressed through botanical medicine treatment as well as hydrotherapy. Olfactory nerve damage may not be regenerable. Some olfactory aberrations, like intensified sense of smell, can be resolved using homeopathic medicine.

Prognosis

If nasal inflammation is the cause of anosmia, the chances of recovery are excellent. However, if nerve damage is the cause of the problem, the recovery of smell is much more difficult.

Resources

BOOKS

Bennett, J. Claude, and Fred Plum, eds. Cecil Textbook of Medicine. Philadelphia: W. B. Saunders Co., 1996.

Harrison's Principles of Internal Medicine. Ed. Anthony S. Fauci, et al. New York: McGraw-Hill, 1997.

"Olfactory Dysfunction." In Current Medical Diagnosis and Treatment, 1996. 35th ed. Ed. Stephen McPhee, et al. Stamford: Appleton & Lange, 1995.

PERIODICALS

Davidson, T. M., C. Murphy, and A. A. Jalowayski. "Smell Impairment. Can It Be Reversed?" Postgraduate Medicine 98 (July 1995): 107-109, 112.


J. Ricker Polsdorfer, MD


Food and Nutrition: anosmia
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Lack or impairment of the sense of smell.

World of the Mind: anosmia
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The loss of the ability to smell. It may be congenital but can be caused by a variety of reasons, including the common cold and lesions in the olfactory tract incurred as a result of head injury.

(Published 1987)

Absence of the sense of smell; characteristic of lesions of the olfactory lobe, peduncle or mucosa. Such deficiencies are difficult to assess in animals.

Wikipedia: Anosmia
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Anosmia
ICD-10 R43.0
ICD-9 781.1
MeSH D000857

Anosmia (ænˈɒz.mi.ə) is a lack of functioning olfaction, or in other words, an inability to perceive odors. Anosmia may be either temporary or permanent. A related term, hyposmia, refers to a decreased ability to smell, while hyperosmia refers to an increased ability to smell. Some people may be anosmic for one particular odor. This is called "specific anosmia" and may be genetically based.

Contents

Diagnosis

Anosmia can be diagnosed by doctors by using scratch-n-sniff odor tests[citation needed] or by using commonly available odors such as coffee, lemon, grape, garlic, vanilla and cinnamon.

Presentation

Anosmia can have a number of detrimental effects. Patients with sudden onset anosmia may find food less appetizing, though congenital anosmics rarely complain about this. Loss of smell can also be dangerous because it hinders the detection of gas leaks, fire, and spoiled food. The common view of anosmia as trivial can make it more difficult for a patient to receive the same types of medical aid as someone who has lost other senses, such as hearing or sight.

Losing an established and sentimental smell memory (e.g. the smell of grass, of the grandparents' attic, of a particular book, of loved ones, or of oneself) has been known to cause feelings of depression.[1]

Loss of olfaction may lead to the loss of libido, though this may not apply to congenital anosmics.[1]

Often people who have congenital anosmia report that they pretended to be able to smell as children because they thought that smelling was something that older/mature people could do, or did not understand the concept of smelling but did not want to appear different from others. When children get older, they often realize and report to their parents that they do not actually possess a sense of smell, often, to the surprise of their parents.[1]

Causes

A temporary loss of smell can be caused by a blocked nose or infection. In contrast, a permanent loss of smell may be caused by death of olfactory receptor neurons in the nose, or by brain injury in which there is damage to the olfactory nerve or damage to brain areas that process smell (see olfactory system). The lack of the sense of smell at birth, usually due to genetic factors, is referred to as congenital anosmia. Anosmia may very occasionally be an early sign of degenerative brain diseases such as Parkinson's disease and Alzheimer's disease. Another specific cause of permanent loss could be from damage to olfactory receptor neurons due to use of certain types of nasal spray, i.e. those that cause vasoconstriction of the nasal microcirculation. To avoid such damage and subsequent risk of loss of smell from vasoconstricting nasal sprays, they should be used for only a short amount of time and only when absolutely necessary. Non-vasoconstricting sprays, such as those used to treat allergy related congestion are safe to use for extended periods of time.[2] Anosmia can also be caused by nasal polyps. These polyps are found in people with allergies, histories of sinusitis & family history. Individuals with cystic fibrosis often develop nasal polyps.

Causes of anosmia include:

Zicam controversy

On June 16, 2009, the U.S. Food and Drug Administration sent a warning letter to Matrixx Initiatives, manufacturer of an over-the-counter nasal spray for the common cold, Zicam. The FDA cited complaints that the product caused Anosmia. The manufacturer strongly denies these allegations, but has recalled the product and has stopped selling it. [13][14]

Associated conditions

Notable anosmic individuals

See also

References

  1. ^ a b c BBC NEWS | UK | Magazine | Sense and scent ability
  2. ^ http://web.archive.org/web/20060101000005/http://www.coldcure.com/anosmia/anosmia.html
  3. ^ Doty RL, Mishra A (2001). "Influences of nasal obstruction, rhinitis, and rhinosinusitis on the ability to smell". Laryngoscope 111: 409–23. 
  4. ^ Doty RL, Yousem DM, Pham LT, Kreshak AA, Lee WW (1997). "Olfactory dysfunction in patients with head trauma". Arch Neurol 54: 1131–1140. 
  5. ^ Doty RL, Deems D, Stellar S (1988). "Olfactory dysfunction in Parkinson's disease: A general deficit unrelated to neurologic signs, disease stage, or disease duration". Neurology 38: 1237–44. 
  6. ^ Murphy C (1999). "Loss of olfactory function in dementing disease". Physiology & Behavior 66: 177–182. doi:10.1016/S0031-9384(98)00262-5. 
  7. ^ Schwartz B, Doty RL, Frye RE, Monroe C, Barker S (1989). "Olfactory function in chemical workers exposed to acrylate and methacrylate vapors". Am J Pub Health 79: 613–618. doi:10.2105/AJPH.79.5.613. 
  8. ^ Rose CS, Heywood PG, Costanzo RM (1992). "Olfactory impairment after chronic occupational cadmium exposure". Journal of Occupational Medicine 34: 600–605. 
  9. ^ Rydzewski B, Sulkowski W, Miarzynaska M (1998). "Olfactory disorders induced by cadmium exposure: A clinical study". Int J Occ Med Env Health 11: 235–245. 
  10. ^ Doty RL, Shaman P, Applebaum SL, Giberson R, Sikorsky L, Rosenberg L (1984). "Smell identification ability: Changes with age". Science 226: 1441–1443. doi:10.1126/science.6505700. PMID 6505700. 
  11. ^ eMedicine - Esthesioneuroblastoma : Article by Pavel Dulguerov
  12. ^ Study Examines Treatment For Olfactory Loss After Viral Infection
  13. ^ www.zicam.com
  14. ^ http://www.cnn.com/2009/HEALTH/06/16/zicam.fda.warning/index.html
  15. ^ [1]
  16. ^ [2]
  17. ^ [3]

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