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Definition

The term anosmia means lack of the sense of smell. It may also refer to a decreased sense of smell. Ageusia, a companion word, refers to a lack of taste sensation. Patients who actually have anosmia may complain wrongly of ageusia, although they retain the ability to distinguish salt, sweet, sour, and bitter—humans' only taste sensations.

Description

Of the five senses, smell ranks fourth in importance for humans, although it is much more pronounced in other animals. Bloodhounds, for example, can smell an odor a thousand times weaker than humans. Taste, considered the fifth sense, is mostly the smell of food in the mouth. The sense of smell originates from the first cranial nerves (the olfactory nerves), which sit at the base of the brain's frontal lobes, right behind the eyes and above the nose. Inhaled airborne chemicals stimulate these nerves.

There are other aberrations of smell beside a decrease. Smells can be distorted, intensified, or hallucinated. These changes usually indicate a malfunction of the brain.

— J. Ricker Polsdorfer, MD



 
 
Dictionary: an·os·mi·a  (ăn-ŏz'mē-ə) pronunciation
n.

Loss of the sense of smell.

[New Latin : Greek an-, without; see a–1 + Greek osmē, odor.]

anosmic an·os'mic adj.
 

Definition

The term anosmia means lack of the sense of smell. It may also refer to a decreased sense of smell. Ageusia, a companion word, refers to a lack of taste sensation. Patients who actually have anosmia may complain wrongly of ageusia, although they retain the ability to distinguish salt, sweet, sour, and bitter—humans' only taste sensations.

Description

Of the five senses, smell ranks fourth in importance for humans, although it is much more pronounced in other animals. Bloodhounds, for example, can smell an odor that is a thousand times weaker than one perceptible by humans. Taste, considered the fifth sense, is mostly the smell of food in the mouth. The sense of smell originates from the first cranial nerves (the olfactory nerves), which sit at the base of the brain's frontal lobes, right behind the eyes and above the nose. Inhaled airborne chemicals stimulate these nerves.

There are other aberrations of smell beside a decrease. Smells can be distorted, intensified, or hallucinated. These changes usually indicate a malfunction of the brain.

Causes and symptoms

The most common cause of anosmia is nasal occlusion caused by rhinitis (inflammation of the nasal membranes). If no air gets to the olfactory nerves, smell will not happen. In turn, rhinitis and nasal polyps (growths on nasal membranes) are caused by irritants such as allergens, infections, cigarette smoke, and other air pollutants. Tumors such as nasal polyps can also block the nasal passages and the olfactory nerves and cause anosmia. Head injury or, rarely, certain viral infections can damage or destroy the olfactory nerves.

Diagnosis

It is difficult to measure a loss of smell, and no one complains of loss of smell in just one nostril. So a physician usually begins by testing each nostril separately with a common, non-irritating odor such as perfume, lemon, vanilla, or coffee. Polyps and rhinitis are obvious causal agents a physician looks for. Imaging studies of the head may be necessary in order to detect brain injury, sinus infection, or tumor.

Treatment

Cessation of smoking is one step. Many smokers who quit discover new tastes so enthusiastically that they immediately gain weight. Attention to reducing exposure to other nasal irritants and treatment of respiratory allergies or chronic upper respiratory infections will be beneficial. Corticosteroids are particularly helpful.

Alternative treatment

Finding and treating the cause of the loss of smell is the first approach in naturopathic medicine. If rhinitis is the cause, treating acute rhinitis with herbal mast cell stabilizers and herbal decongestants can offer some relief as the body heals. If chronic rhinitis is present, this is often related to an environmental irritant or to food allergies. Removal of the causative factors is the first step to healing. Nasal steams with essential oils offer relief of the blockage and tonification of the membranes. Blockages can sometimes be resolved through naso-specific therapy—a way of realigning the nasal cavities. Polyp blockage can be addressed through botanical medicine treatment as well as hydrotherapy. Olfactory nerve damage may not be regenerable. Some olfactory aberrations, like intensified sense of smell, can be resolved using homeopathic medicine.

Prognosis

If nasal inflammation is the cause of anosmia, the chances of recovery are excellent. However, if nerve damage is the cause of the problem, the recovery of smell is much more difficult.

Resources

BOOKS

Bennett, J. Claude, and Fred Plum, eds. Cecil Textbook of Medicine. Philadelphia: W. B. Saunders Co., 1996.

Harrison's Principles of Internal Medicine. Ed. Anthony S. Fauci, et al. New York: McGraw-Hill, 1997.

"Olfactory Dysfunction." In Current Medical Diagnosis and Treatment, 1996. 35th ed. Ed. Stephen McPhee, et al. Stamford: Appleton & Lange, 1995.

PERIODICALS

Davidson, T. M., C. Murphy, and A. A. Jalowayski. "Smell Impairment. Can It Be Reversed?" Postgraduate Medicine 98 (July 1995): 107-109, 112.


J. Ricker Polsdorfer, MD


 

Lack or impairment of the sense of smell.

 

Absence of the sense of smell; characteristic of lesions of the olfactory lobe, peduncle or mucosa. Such deficiencies are difficult to assess in animals.

 
Wikipedia: anosmia
Name of Symptom/Sign:
Anosmia
Classifications and external resources
ICD-10 R43.0
ICD-9 781.1

Anosmia is the lack of olfaction, or a loss of the ability to smell. It can be either temporary or permanent. A related term, hyposmia, refers to a decrease in the ability to smell, while hyperosmia refers to an increased ability to smell. Some people may be anosmic for one particular odor. This is called "specific anosmia" and may be genetically based.

While termed as a disability, anosmia is often viewed in the medical field as a trivial problem. This is not always the case—esthesioneuroblastoma is a very rare cancerous tumor originating in or near the olfactory nerve.

Diagnosis

Anosmia can be diagnosed by doctors by using scratch-n-sniff odor tests or by using commonly available odors such as coffee, lemon, grape, vanilla and cinnamon.

Smell vs. taste

It should be emphasized that there are no more than 6 distinctive tastes: salty, sour, sweet, bitter, umami and possibly fatty acids. The 10,000 different scents which humans usually recognize as 'tastes' are often actually 'flavor', which many people who can smell confuse with taste. This sense of 'flavor' is greatly diminished by a loss of the sense of smell, often causing those with sudden onset anosmia a great deal of concern when all food suddenly loses its flavor. Congenital anosmics often have a much more developed sense of taste than those who could smell at some point in their lives, and can enjoy food just as much as someone who could smell.

Presentation

Anosmia can have a number of detrimental effects. Patients with sudden onset anosmia may find food less appetizing, though congenital anosmics rarely complain about this. Loss of smell can also be dangerous because it hinders the detection of gas leaks, fire, body odor, and spoiled food. The common view of anosmia as trivial can make it more difficult for a patient to receive the same types of medical aid as someone who has lost other senses, such as hearing or sight.

Losing an established and sentimental smell memory (e.g. the smell of grass, of the grandparents' attic, of a particular book, of loved ones, or of oneself) has been known to cause feelings of depression.[1]

Loss of olfaction may lead to the loss of libido, even to the point of impotency, which often preoccupies younger anosmic men.[2][dubious ]

Often people who have congenital anosmia report that they pretended to be able to smell as children because they thought that smelling was something that 'big people' could do, or did not understand the concept of smelling but did not want to appear different from others. When children get older, they often realize and report to their parents that they do not actually possess a sense of smell, much to the surprise of their parents.[citation needed]

Causes

A temporary loss of smell can be caused by a stuffy nose or infection. In contrast, a permanent loss of smell may be caused by death of olfactory receptor neurons in the nose, or by brain injury in which there is damage to the olfactory nerve or damage to brain areas that process smell (see olfactory system). The lack of the sense of smell at birth, usually due to genetic factors, is referred as congenital anosmia. Anosmia may very occasionally be an early sign of degenerative brain diseases such as Parkinson's disease and Alzheimer's disease. Another specific cause of permanent loss could be from damage to olfactory receptor neurons due to use of certain types of nasal spray, i.e. those that cause vasoconstriction of the nasal microcirculation. To avoid such damage and subsequent risk of loss of smell from vasoconstricting nasal sprays, they should be used for only a short amount of time and only when absolutely necessary. Non-vasoconstricting sprays, such as those used to treat allergy related congestion are safe to use for extended periods of time.[3]

Anosmia can also be caused by nasal polyps. These polyps are found in people with allergies, histories of sinusitis & family history. Individuals with Cystic Fibrosis often develop nasal polyps.

Associated conditions


See also

Notable Anosmiacs

References

  1. ^ news.bbc.co.uk/2/hi/uk_news/magazine/6199605.stm.
  2. ^ news.bbc.co.uk/2/hi/uk_news/magazine/6199605.stm.
  3. ^ www.coldcure.com/anosmia/anosmia.html.
  4. ^ Doty RL, Mishra A (2001). "Influences of nasal obstruction, rhinitis, and rhinosinusitis on the ability to smell". Laryngoscope 111: 409–23. 
  5. ^ Doty RL, Yousem DM, Pham LT, Kreshak AA, Lee WW (1997). "Olfactory dysfunction in patients with head trauma". Arch Neurol 54: 1131–1140. 
  6. ^ Doty RL, Deems D, Stellar S (1988). "Olfactory dysfunction in Parkinson's disease: A general deficit unrelated to neurologic signs, disease stage, or disease duration". Neurology 38: 1237–44. 
  7. ^ Murphy C (1999). "Loss of olfactory function in dementing disease". Physiology & Behavior 66: 177–182. 
  8. ^ Schwartz B, Doty RL, Frye RE, Monroe C, Barker S (1989). "Olfactory function in chemical workers exposed to acrylate and methacrylate vapors". Am J Pub Health 79: 613–618. 
  9. ^ Rose CS, Heywood PG, Costanzo RM (1992). "Olfactory impairment after chronic occupational cadmium exposure". Journal of Occupational Medicine 34: 600–605. 
  10. ^ Rydzewski B, Sulkowski W, Miarzynaska M (1998). "Olfactory disorders induced by cadmium exposure: A clinical study". Int J Occ Med Env Health 11: 235–245. 
  11. ^ Doty RL, Shaman P, Applebaum SL, Giberson R, Sikorsky L, Rosenberg L (1984). "Smell identification ability: Changes with age". Science 226: 1441–1443. 
  12. ^ www.emedicine.com/med/topic748.htm.

External links


 
 

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Medical Encyclopedia. © 2006 through a partnership of Answers Corporation. All rights reserved.  Read more
Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2007. Published by Houghton Mifflin Company. All rights reserved.  Read more
Neurological Disorder. Gale Encyclopedia of Neurological Disorders. Copyright © 2005 by The Gale Group, Inc. All rights reserved.  Read more
Food and Nutrition. A Dictionary of Food and Nutrition. Copyright © 1995, 2003, 2005 by A. E. Bender and D. A. Bender. All rights reserved.  Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Anosmia" Read more

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