n.
- Hostility that results in active resistance, opposition, or contentiousness. See synonyms at enmity.
- The condition of being an opposing principle, force, or factor: the inherent antagonism of capitalism and socialism.
- Biochemistry. Interference in the physiological action of a chemical substance by another having a similar structure.
The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.