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(¦ap·ə¦prō′tēn)

(biochemistry) The protein portion of a conjugated protein exclusive of the prosthetic group.


 
 
Medical Dictionary: ap·o·pro·tein
(ăp'ə-prō'tēn', -tē-ĭn)
n.

A polypeptide that combines with a prosthetic group to form a conjugated protein.

 

The protein moiety of a molecule or complex, as of a lipoprotein.

 
Wikipedia: apoprotein

An apoprotein is a protein without its characteristic prosthetic group.

Apoproteins are lipid-binding proteins present in chylomicrons, absorbed by Enterocytes within the small intestines and colonocytes in the colon. Following initial absorbtion, they are then exocytosed into the lymphatic system and into venous blood along with Apoprotein A, which is found in HDL cholesterol or High-density lipoprotein cholesterol.

Apoprotein A facilitates cholesterol uptake by the liver and other tissues, allowing HDL cholesterol to help transport other cholesterol out of the blood plasma, hence being considered a "healthy cholesterol". Furthermore, a high protein to lipid ratio in HDL cholesterol due to Apoprotein A increases its density.

Apoprotein B, found in LDL cholesterol or Low-density lipoprotein cholesterol, combines with receptors that bring LDL cholesterol into other cells of the body. A low protein to lipid ratio in LDL cholesterol due to Apoprotein B decreases its density.


See also

Apolipoprotein


 
 

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Sci-Tech Dictionary. McGraw-Hill Dictionary of Scientific and Technical Terms. Copyright © 2003, 1994, 1989, 1984, 1978, 1976, 1974 by McGraw-Hill Companies, Inc. All rights reserved.  Read more
Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Apoprotein" Read more

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