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An apoprotein is a polypeptide portion of a conjugated protein.

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An apoprotein is a polypeptide portion of a conjugated protein.

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An apoaequorin is an apoprotein found in the photoprotein aequorin.

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Definition

Apolipoprotein CII (apoCII) is a protein found in large fat particles absorbed from the gastrointestinal tract. It is also found in very low density lipoprotein (VLDL), which is made up of mostly triglycerides.

This article discusses the test used to check for apoCII in a sample of your blood.

Alternative Names

ApoCII; Apoprotein CII; ApoC2

How the test is performed

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

How to prepare for the test

You may be told not to eat or drink anything for 4 - 6 hours before the test.

How the test will feel

When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed

ApoCII measurements can help to determine the specific type or cause of high blood lipids (hyperlipidemia).

Normal Values

Usually, apoCII is reported as present or absent. If the specific level is measured, the normal value may vary according to the institution performing the test.

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What abnormal results mean

High levels of apoCII may be due to:

Low apoCII levels are seen in persons with a rare condition called familial apoprotein CII deficiency. This causes chylomicronemia syndrome.

What the risks are

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

  • Excessive bleeding
  • Fainting or feeling light-headed
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)
References

Mahley RW, Weisgraber KH, Bersot TP. Disorders of lipid metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.

Semenkovich CF. Disorders of lipid metabolism. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 217.

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Definition

Apolipoprotein B100 (apo B100) is a protein that plays a role in moving cholesterol around your body. It is a form of low density lipoprotein(LDL).

This article discusses the test used to measure the level of apoB100 in the blood.

Alternative Names

ApoB100; Apoprotein B100

How the test is performed

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

How to prepare for the test

Your health care provider may tell you not to eat or drink anything for 4 - 6 hours before the test.

How the test will feel

When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed

Most often, this test is done to help determine the cause or specific type of hyperlipidemia.

Normal Values

The normal range is 40 - 125 mg/dL.

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What abnormal results mean

An abnormal result may mean you have high lipid levels (hyperlipidemia).

Other disorders that may be associated with high apoB100 levels include angina pectoris and heart attack.

See also: Familial combined hyperlipidemia

What the risks are
  • Excessive bleeding
  • Fainting or feeling light-headed
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)
  • Multiple punctures to locate veins
Special considerations

Apolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown.

References

Mahley RW, Weisgraber KH, Bersot TP. Disorders of lipid metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.

Semenkovich CF. Disorders of lipid metabolism. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 217.

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A (aminoacyl) site

A form DNA

a(n)-

A-factor

A-protein

A23187

Ab initio gene prediction

ab-

abaxial

Abbreviated New Drug Application

ABC proteins

ABCD rating

abdomen

abdominal

abetalipoproteinemia

abiogenesis

abiotic

abiotic factors

abiotic stress

ablation

abnormal

ABO blood group

aboral end

abortion

abortive

abortive transduction

abscess

abscise

abscisic acid

abscission zone

absolute zero

absorbance optics

absorptive endocytosis

abyssal zone

abzyme

acanthocarpa

acanthodes

acariasis

acaricide

acarodomatia

acaulescent

accelerated run

acceptor

acceptor arm

acceptor end

acceptor stem

accessory cell

accessory pigment

accessory protein

acclimation

accommodation

accrete

accumbent

accuracy

acellular

acellular vaccine

acentric chromosome

acentric fragment

aceriform

acerose

acervulus

acesulfames

acetaminophen

acetic acid

acetyl group

acetylcholine

acetylcholine receptor channel

Acetylcholinesterase (AChE)

Achaete-scute complex (AS-C)

achene

achenecetum

achenocarp

Achilles tendon

achiral

achlamydeous

achlorophyllous

achondroplasia

acid

Acid phosphatase

acid rain

acid-base reaction

acid-ionization constant

acidic oxide

acidosis

acini

acne

acoelomate

acre

acrocentric

Acrocentric chromosome

acrosomal vesicle

acrosome

ACTH

actin

action potential

activate

Activated Support

activation energy

activation energy (deltaG)

Activator and Dissociation

active immunity

active site

active transport

actuator

acute

acyl-CoA

acyl-CoA synthetase

ad-

adaptation

adaptive landscape

adaptive peak

adaptive radiation

additive genetic effects

additive genetic variance

additive model

adductor longus

adenine

adenocarcinoma

adenosine

adenosine deaminase deficiency

adenosine triphosphate (ATP)

Adenovirus

adfluvial

ADH

adhesion

adipocyte

adipose tissue

adjacent segragation

adjacent-1 segregation

adjacent-2 segregation

adjuvant

ADME

ADMETox drug screening

adrenal

adrenal cortex

adrenal glands

adrenal medulla

adrenalectomy

adrenaline

adrenergic

adrenergic receptors

adrenocorticotropic hormone

adult-onset

adventitious root

aerial root

aerobic

aerobic respiration

Aeronomy

affected

affected relative pair

afferent

afferent arteriole

affinity

agar

agarose

age structure

agent

agglutination

aggrade

aggregate

aggregates

aggregation technique

aggresome

agitator

agonist

Agricultural Development and Advisory Service

Agrobacterium

AIDS-related complex

AKT

Alagille Syndrome

Alanine

albedo

albino

albumen

albumin

alcoholic fermentation

Aldehyde dehydrogenase

aldosterone

algae

alkali metal

alkaline earth metal

alkaline phosphatase

alkalosis

alkylating agent

allantois

allele

allele frequency

allele specific hybridization

Allele specific polymerase chain reaction

Allele specific polymerase chain reaction (AS-PCR)

allelic

allelic exclusion

allergen

allergy

allergy mediator

allo-

allogeneic

allogeneic antigen

allogeneic graft

allogenic

allograft

allometric growth

allopatric speciation

allopolyploid

allosteric change

allosteric protein

allotype

alloy

allozygosity

allozyme

alpha globulin

alpha helix

Alpha-fetoprotein

alpha-linolenic acid

Alphamethylstyrene

alpine

altered

alternate segregation

alternation of generations

alternative pathway

alternative splicing

altruism

Alu family

alveolar duct

alveolar epithelium

alveolar ventilation

alveolate

alveoli

Alzheimer's Disease

amber codon

amber suppressor

ambi-

ambient

Ames test

amino acid

amino group

aminoacyl-tRNA

aminoacyl-tRNA synthetase

Aminoglycosides

aminotransferase

ammonia

amniocentesis

Amniography

amnion

amniote

Amniotic fluid

amoebocyte

amorph

Amphetamine

amphi-

amphibian

amphidiploid

Amphimixis

amphipathic

amphoteric

amphotropic virus

amplexus

Amplicon

amplification

amplification of DNA

Amplified fragment length polymorphism

ampoule

ampulla

ampullae

amu

amygdala

amylase

amyloid

amyloidogenesis

amyloidosis

amylose

Amyotrophic Lateral Sclerosis

amyotrophy

anabolic

anabolism

anadromous

anaerobe

anaerobic respiration

anagenesis

analog

analogous enzymes

analogous structure

analogy

analysis

analysis of variance

analyst

Analyte

analytical chemistry

anaphase

anaphase I

anaphase II

anaphylatoxin

anaphylaxis

anastomose

anatomy

anaxonal neuron

ancestor

ANDA

androecium

androgen

androgen receptor (AR)

anemia

anencephaly

aneuploid

aneuploidy

angiogenesis

angiosperm

angiotensin

Angstrom (Å )

animal

animal behavior

animal breeding

animal model

Animalia

anion

anisogamous

anisogamy

Anlage

annealing

annelid

Annotation

annual

annual rings

annulate

anode

ANOVA

Antagonist

antagonistic muscles

antagonistic pleiotropy

anterior

anterior horn

anther

antheridia

anthesis

anthocyanin

Anthropometric

anti-

anti-hypertensive drugs

anti-inflammatory cytokines

anti-oncogene

anti-tumor drug

antiarrhythmic

antiasthmatic

antibiotic

antibiotic resistance

antibody

antibody assays

antibody formation

antibody specificity

Anticipation

anticipatory postural activity

anticoagulant

anticoding strand

anticodon

anticonvulsant

antidiuretic hormone

antigen

antigen binding site

antigen processing

antigen receptor

antigen-presenting cell (APC)

antigenic determinant

antigenic switching

antimicrobial agent

antimorph

antioxidant

antiparallel

antipyrine

antisense

antisense RNA

antiterminator protein

anus

aorta

AP endonuclease

AP site

AP-1

APC

APCI

apex

apical meristems

Apogamy

apolipoprotein

Apomixis

apoplast

apoplastic

apoprotein

apoptosis

appendicular skeleton

appendix

Application

aprotinin

aqueous humor

aqueous solution

aquifer

arachidonic acid

Archaea

archegonia

archenteron

archeocyte

arcuate nucleus

arcuatus

area postrema

Arginine

Argon

armpit

Arrayed library

Arrestins

Arrhenius acid

arrow diagram

arterial

Arteriogram

arteriole

artery

arthritis

arthro

arthropod

artifact

artificial insemination (A.I.)

artificial selection

ascending limb

ascomycete

ascospore

ascus (asci)

Asparagine

Aspartame

Aspartic acid

aspiration

aspirin

assay

Assembly

assignment test

assortative mating

aster

asthma

astrocyte

astrocytosis

asymmetric division

asymptomatic

ataxia

ataxia-telangiectasia

atmospheric pressure chemical ionization

atom

atomic mass

atomic mass unit

atomic number

atomic weight

atopy

ATP synthase

atrazine

Atrial natriuretic factor (ANF)

atrial natriuretic factor receptors

atriopore

atrioventricular node

atrioventricular valve

atrium

atrophy

attached X

attenuation

attenuator

attenuator stem

attract

auditory nerve

auricle

autoantibody

Autocatalytic Reaction

autochthonous

autoecology

autogamy

autograft

autoimmune disease

autoimmunity

autologous

automixis

autonomic nervous system

autonomous replication sequence (ARS)

autonomous specification

autopolyploid

autoradiography

autoregulation

autosomal dominant

autosomal recessive

autosomal set

autosome

autotroph

autozygosity

autozygous

auxin

auxotroph

auxotrophic mutant

average

average molecular weight

avidity

Avogadro's law

Avogadro's number (N)

Avuncular relationship

axial skeleton

axil

axilla

axon

axoneme

azoic

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