
[New Latin bactērium, from Greek baktērion, diminutive of baktron, rod.]
A common gut bacteria may be a major cause of rheumatoid arthritis—Independent, 1991.
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Van Leeuwenhoek and A Microscope |
| Antoine-Joseph (Adolphe) Sax | |
| Antonio Salieri |
From our Archives: Today's Highlights, October 24, 2005
A scientist may be able to see a single bacterium through a microscope.
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| bactoprenol, baculovirus, bafilomycin A1 |
Pl. bacteria [L.] any prokaryotic microorganism. Bacteria are single-celled microorganisms that differ from all other organisms (the eukaryotes) in lacking a true nucleus and organelles such as mitochondria, chloroplasts and lysosomes. Their genetic material consists of a single double-stranded DNA molecule, whereas the genetic material of eukaryotes consists of multiple chromosomes, which are complex structures of DNA and protein.
Bacteria reproduce by binary fission and generally have a very high rate of population growth and mutation. Genetic material can be transferred between bacteria by three processes: transformation (absorption of naked DNA), transduction (transfer by a temperate bacteriophage), and conjugation (transfer by independently replicating DNA molecules, called plasmids). Some bacteria can also form spores, dehydrated forms that are relatively resistant to heat, cold, lack of water, toxic chemicals and radiation.
Most bacteria have a rigid cell wall outside of the cell membrane primarily composed of a dense layer of peptidoglycan, a network of polysaccharide chains with polypeptide cross-links. Some antimicrobial agents, the penicillins and cephalosporins, act by interfering with peptidoglycan synthesis.
Bacteria can have any of three types of external structures: flagella, which are rotating locomotor organelles; pili or fimbriae, which are minute filamentous appendages; and a capsule, which is a layer of gelatinous material around the cell. Large pili called sex pili are involved in conjugation while other pili are involved in adherence of bacteria to mucosal surfaces. The capsule is associated with virulent strains of bacteria and protects the bacterium from phagocytosis. See also bacteria.
