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Basket cell

 
Sci-Tech Dictionary: basket cell
(′bas·kət ′sel)

(histology) A type of cell in the cerebellum whose axis-cylinder processes terminate in a basketlike network around the cells of Purkinje.


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Medical Dictionary: bas·ket cell
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(băs'kĭt)
n.
  1. Any of the neurons in the cerebellum whose terminal axons form a basketlike network around another cell.
  2. A myoepithelial cell with branching processes that occurs basal to the secretory cells of certain salivary and lacrimal gland alveoli.
Wikipedia: Basket cell
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Neuron: Basket cell
Basket cell - Transverse section of a cerebellar folium (Basket cell labeled at bottom left)
Transverse section of a cerebellar folium (Basket cell labeled at bottom left)
Location Cerebellum
Function Inhibitory interneuron
Morphology multipolar
Presynaptic connections Parallel fibers
Postsynaptic connections Purkinje cells
NeuroLex ID nifext_160

Basket cells are inhibitory GABAergic interneurons found in several brain regions: the molecular layer of the cerebellum, the hippocampus, and the cortex. In the cerebellum, they synapse on the cell bodies of Purkinje cells, and are multipolar and stellate, with freely branching dendrites, which are dilated and knotty. Hippocampal basket cells target somata and proximal dendrites of pyramidal neurons. Cortical[1] and hippocampal basket cells are parvalbumin-expressing and fast-spiking. In the cortex, basket cells have sparsely branched axons giving off small pericellular, basket-shaped elaborations at several intervals along their length. There are three types of basket cells in the cortex, the small, large and nest type[2]: The axon of a small basket cell arborizes in the vicinity of that same cells dendritic range. In contrast, large basket cells innervate somata in different cortical columns. The nest basket cells are an intermediate form of the small and large cells, their axons are confined mainly to the same cortical layer as their somata.

Microcircuitry of the cerebellum. Excitatory synapses are denoted by (+) and inhibitory synapses by (-).
Basket cell labeled BC

External links

Footnotes

  1. ^ Contreras D.(2004). "Electrophysiological classes of neocortical neurons", Neural Networks 17(5-6), pp. 633-46.
  2. ^ Fox, K. "Barrel Cortex", Cambridge University Press, pp. 55-56

References

  • Jones, E. G. & Hendry, S. H.(1984). "Basket cells. In: Cellular components of the cerebral cortex", New York: Plenum Press, pp. 309-336



 
 
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