In January 1565, the last Hindu kingdom of South India fell
after the Battle of Talikota.
In February, Spanish Conquistador Miguel Lopez de Legazpi landed
in the Philippines; he founded the first Spanish settlement in the
Philippines later that year.
In March, the city of Rio de Janeiro was founded.
In May, the Siege of Malta began; it ended in September.
In July, Mary, Queen of Scots married Henry Stuart, Lord
Darnley, technically giving him precedence.
In August, St. Augustine, Florida was founded; it is the oldest
remaining European settlement in the US.
In December, Pope Pius IV died.