Bence Jones proteins normally are not present in the urine.

Urine is the best specimen in which to look for Bence Jones proteins

.Multiple myeloma, a tumor of plasma cells, is the disease most often linked with Bence Jones proteins.Physicians use Bence Jones proteins testing to diagnose the disease as well as to check how well the disease is responding to treatment.

heat and acetic acid test

put 5ml of concentrated hydrochloric acid in a clear tube.carefully add 3ml of test urine to make a good interface without mixing the two.a white curdy precipitate at the interface indicates presence of bence Jones protein