(inorganic chemistry) Bi(C7H5O)3Bi2O3 A white powder that is insoluble in ethanol and water; used in medicine and as a fungicide for tobacco crops.
| Sci-Tech Dictionary: bismuth subsalicylate |
(inorganic chemistry) Bi(C7H5O)3Bi2O3 A white powder that is insoluble in ethanol and water; used in medicine and as a fungicide for tobacco crops.
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trade names: Bisamatrol, Pepto-Bismol; drug class: antidiarrheal; action: mechanism of action unknown; uses: treatment of diarrhea, prevention of diarrhea when traveling.
| Wikipedia: Bismuth subsalicylate |
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Bismuth subsalicylate
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| Systematic (IUPAC) name | |
| 2-hydroxy-2H,4H-benzo[d]1,3-dioxa-2-bismacyclohexan-4-one | |
| Identifiers | |
| CAS number | 14882-18-9 |
| ATC code | none |
| PubChem | 16682734 |
| ChemSpider | 17215772 |
| Chemical data | |
| Formula | C7H5BiO4 |
| Mol. mass | 362.093 g/mol |
| SMILES | eMolecules & PubChem |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral |
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Bismuth subsalicylate, with a chemical formula C7H5BiO4,[1] is a drug used to treat nausea, heartburn, indigestion, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. Commonly known as pink bismuth, it is the active ingredient in popular medications such as Pepto-Bismol and modern (since 2003) Kaopectate.
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As a derivative of salicylic acid, bismuth salicylate displays anti-inflammatory action and also acts as an antacid.
There are some adverse effects. It can cause a black tongue and black stools in some users of the drug, when it combines with trace amounts of sulfur in saliva and the gastrointestinal tract.[2] This discoloration is temporary and harmless.
Some of the risks of salicylism can apply to the use of bismuth subsalicylate.[3][4]
Children should not take medication with bismuth subsalicylate while recovering from influenza or chicken pox, as epidemiologic evidence points to an association between the use of salicylate-containing medications during certain viral infections and the onset of Reye's syndrome.[5] For the same reason, it is typically recommended that nursing mothers not use medication containing bismuth subsalicylate (such as Pepto-Bismol) because small amounts of the medication are excreted in breast milk and pose a theoretical risk of Reye's syndrome to nursing children.[6]
While bismuth is technically radioactive, its half life is so long, on the order of hundreds of billions of years,[7] that its radioactivity presents absolutely no threat under all medical and other ordinary purposes.
Bismuth subsalicyclate is the only active ingredient in an over the counter medication that will actually leave a shiny metal slag behind after being completely burnt with a blow torch.[8]
This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
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