I am 73, and my resting heart rate typically is 42-48 beats per minute. I am aware of no negative symptoms. Three times a week I do a power-walk of four miles, averaging about 12 to 12 1/2 minutes per mile, with no ill effects. My answer is "yes."
And I am a 29 y/o male, 173 cm in height of 100 kg with a resting heart rate of 39-45 (sleeping), and on an average week I do the following without any ill effects (no fatigue or anything):
- run 3-4 times (average distance of 3,5 km) - high intensity
- ride my bike 65-80 km - moderate-high intensity
- walk 20-25 km - moderate intensity
- 2-4x13 minutes on a rowing machine - high intensity
- moderate strength based exercises (push-ups, sit-ups, and the like) of probably 15-20 minutes spread out over the week
My answer is also "yes"