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in the 1950's

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in the 1950's

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Watson and Crick came up with the base-pairing rule for nucleic acids using Chargaff's rule that in DNA the percentages of adenine and thymine are equal, and the percentages of guanine and cytosine are equal.

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Erwin Chargaff

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adenine/thymine=guanine/cytosine

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Chargaff's rule is adenine ALWAYS goes with thymine

guanine ALWAYS goes with cytosine

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