Chlamydia trachomatis
n.pr
An organism that lives in the conjunctivae of the eye and the epithelium of the urethra and cervix and is responsible for conjunctivitis, lymphogranuloma venereum, and trachoma.
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An organism that lives in the conjunctivae of the eye and the epithelium of the urethra and cervix and is responsible for conjunctivitis, lymphogranuloma venereum, and trachoma.
A species of Chlamydia that causes trachoma, inclusion conjunctivitis, lymphogranuloma venereum, nonspecific urethritis, and proctitis in humans.
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C. trachomatis inclusion bodies (brown) in a McCoy cell culture.
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| Chlamydia trachomatis Busacca, 1935 |
Chlamydia trachomatis is one of three bacterial species in the genus Chlamydia, family Chlamydiaceae, class Chlamydiae, phylum Chlamydiae, domain Bacteria. C. trachomatis is a gram-negative bacteria that has only been found living inside the cells of humans, causing the following conditions:
In men
In women
In both sexes
C. trachomatis has also been detected in some patients with temporomandibular joint (TMJ) disease. It may be treated with any of several antibiotics: azithromycin, erythromycin or doxycycline/tetracycline.
C. trachomatis was the first chlamydial agent discovered in humans. It comprises two human biovars: trachoma and lymphogranuloma venereum (LGV). Many, but not all, C. trachomatis strains have an extrachromosomal plasmid. Chlamydia species are readily identified and distinguished from other chlamydial species using DNA-based tests. Most strains of C. trachomatis are recognized by monoclonal antibodies [mAbs] to epitopes in the VS4 region of MOMP. However, these mAbs may also crossreact with the other two Chlamydia species, Chlamydia suis and Chlamydia muridarum.
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