cholestyramine

n.
A drug used to lower serum cholesterol levels and treat itching associated with jaundice through its ability to bind intestinal bile acids and promote their excretion.

[CHOLE(STEROL) + STYR(ENE) + AMINE.]

Drug used to treat hyperlipidaemia by complexing bile salts in the intestinal lumen and increasing their excretion, so increasing their synthesis from cholesterol.

n

trade names: Questran, Cholybar; drug class: anti-lipemic; action: absorbs, combines with bile acids to form insoluble complex that is excreted through the feces; lowers cholesterol levels; uses: primary hypercholesterolemia, pruritus associated with biliary obstruction, diarrhea caused by excess bile acid, digitalis toxicity, xanthomas.

Brand names: LoCHOLEST®LoCHOLEST® LightPrevalite®Questran®Questran® Light

Chemical formula:

Español:
• Colestiramina, Polvo para suspensión oral

Cholestyramine Powder for Oral suspension

What is this medicine?

CHOLESTYRAMINE (koe LESS tir a meen) is used to lower cholesterol in patients who are at risk of heart disease or stroke. This medicine is only for patients whose cholesterol level is not controlled by diet.
 
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
•blocked bile duct
•an unusual or allergic reaction to cholestyramine, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding

How should I use this medicine?

Do not take this medicine in the dry form. It must be mixed with a liquid before swallowing. Follow the directions on the prescription label. Place the powder in a glass or cup. Add between 2 and 6 ounces of fluid. This can be water, milk, pulpy fruit juice, fluid soup, or other liquid. Mix well and drink all of the liquid. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What may interact with this medicine?

•diuretics
•female hormones, like estrogens or progestins and birth control pills
•heart medicines such as digoxin or digitoxin
•penicillin G
•phenobarbital
•phenylbutazone
•phytonadione
•propranolol
•tetracycline antibiotics
•thyroid hormones
•vitamin A
•vitamin D
•vitamin E
•warfarin

Take other drugs at least 1 hour before or 4 hours after this medicine, to avoid decreasing their absorption.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Your blood fats and other tests will be measured from time to time.

This medicine is only part of a total cholesterol-lowering program. Your health care professional or dietician can suggest a low-cholesterol and low-fat diet that will reduce your risk of getting heart and blood vessel disease. Avoid alcohol and smoking, and keep a proper exercise schedule.

To reduce the chance of getting constipated, drink plenty of water and increase the amount of fiber in your diet. Ask your doctor or health care professional for advice if you are constipated.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
•bloody or black, tarry stools
•severe stomach pain with nausea and vomiting
•unusual bleeding

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•constipation or diarrhea
•dizziness
•headache
•heartburn, indigestion
•nausea, vomiting
•perianal irritation

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

A bile-acid binding resin used to treat hyperlipidemia and as an absorbent to prevent intestinal absorption of toxins.