SHYUKGHKY

1881

Aldol condensation is the reaction of two aldehydes in the presence of a basic catalyst. The aldol condensation leads to an aldol product, in which an hydroxyl group is attached to the beta carbon of an aldehyde.

Claisen condensation is similar to aldol condensation, but is involves two esters instead of two aldehydes. The product of a Claisen condensation is a beta-keto-ester, a compound characterized by an ester with its alpha carbon being a ketone.

Of course,The Claisen Condensation is typically the reaction between two esters, in the presence of base, leading to formation of an ester enolate that reacts with an uncharged ester, thereby displacing it's "alcohol part" as the leaving group. The sequence leads to the formation of beta ketoesters.

The intramolecular (cyclic) version of the Claisen Condensation is known as the Dieckmann Condensation, and is illustrated through the article, "Dieckmann Condensation Missing Piece."

The Claisen-Schmidt reaction involves the condensation of two carbonyl compounds, typically an aldehyde and a ketone, to form an α,β-unsaturated carbonyl compound. In contrast, aldol condensation involves the condensation of an aldehyde or ketone with itself to form a β-hydroxy carbonyl compound. The key difference is the presence of two different carbonyl compounds in the Claisen-Schmidt reaction, while aldol condensation involves one carbonyl compound reacting with itself.