The difference between a run on and a comma splice is that a run on just keeps going and a comma splice is when you use a comma incorrectly

A comma splice is such a comma, when it collects two independent clauses are connected by only a comma. The following example illustrates a comma splice: the job is hard, get some rest.

A sentence splice (alternately, comma splice) is when 2 independent clauses are joined by a comma. This is not grammatically correct. To fix a sentence splice, you can either change the comma to a semicolon, or you can add a coordinating conjunction after the comma (for, and, nor, but, or, yet, so).

A sentence splice (alternately, comma splice) is when 2 independent clauses are joined by a comma. This is not grammatically correct. To fix a sentence splice, you can either change the comma to a semicolon, or you can add a coordinating conjunction after the comma (for, and, nor, but, or, yet, so).

A comma splice is the attempt to join two independent clauses with a comma without a coordinating conjunction. For example, "She walked the dog last night, today she fed it."