There is currently no way to prevent complement deficiencies.

Complement deficiencies are a group of disorders in which there is a reduced level of specific proteins, complement, involved in proper immune functioning.

symptoms of complement deficiency diseases (like hereditary angioedema, paroxysmal nocturnal hemoglobinuria, or leukocyte adhesion deficiency syndrome) include abdominal and back pain, skin infections, edema or swelling of the face

There is no alternative treatment for complement problems.

If an autoimmune disease develops, like lupus, the person may lose weight, suffer from a rash, and have joint pain.