| Identifiers | |
| Symbol | CCNE1 |
| Alt. Symbols | CCNE |
| Entrez | 898 |
| HUGO | 1589 |
| OMIM | 123837 |
| RefSeq | NM_001238 |
| UniProt | P24864 |
| Other data | |
| Locus | Chr. 19 q12 |
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cyclin E2
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| Identifiers | |
| Symbol | CCNE2 |
| Entrez | 9134 |
| HUGO | 1590 |
| OMIM | 603775 |
| RefSeq | NM_057749 |
| UniProt | O96020 |
| Other data | |
| Locus | Chr. 8 q22.1 |
Cyclin E is a member of the cyclin family.
Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase. The Cyclin E/CDK2 complex phosphorylates p27Kip1 (an inhibitor of Cyclin D), tagging it for degradation, thus promoting expression of Cyclin A, allowing progression to S phase.
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