cytidine

A white crystalline nucleoside, C₉H₁₃N₃O₅, composed of one molecule each of cytosine and ribose.

[CYT(O)– + –ID(E) + –INE².]

A nucleoside comprising one cytosine molecule linked to a D-ribose sugar molecule. The derived nucleotides, cytidine mono-, di-, and triphosphate (CMP, CDP, and CTP respectively) participate in various biochemical reactions, notably in phospholipid synthesis.

Cytidine

A nucleoside, cytosine riboside; a constituent of RNA and cytidine nucleotides.

• c. 5′-triphosphate — CTP; pyrimidine-nucleotide base involved in the structure of the nucleic acids, DNA and RNA, in the activation of sugars, and in phospholipid synthesis.

Cytidine
IUPAC name	4-​amino-​1-​[3,​4-​dihydroxy-​5-​(hydroxymethyl)​tetrahydrofuran-​2-​yl]​pyrimidin-​2-​one
Identifiers
CAS number	[65-46-3]
PubChem	6175
MeSH	Cytidine
SMILES	NC1=NC(=O)N(C=C1) [C@@H]2O[C@H](CO)C(O)C2O
Properties
Molecular formula	C9H13N3O5
Molar mass	243.22 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references

Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N₁-glycosidic bond. Cytidine is a component of RNA.

If cytosine is attached to a deoxyribose ring, it is known as a deoxycytidine.

Dietary sources of cytidine

Dietary sources of cytidine include foods with high RNA (ribonucleic acid) content,^[1] such as organ meats, Brewer's yeast, as well as pyrimide-rich foods such as beer. During digestion, RNA-rich foods are broken-down into ribosyl pyrimidines (cytidine and uridine), which are absorbed intact.^[1] In humans, dietary cytidine is converted into uridine, ^[2] which is probably the compound behind cytidine's metabolic effects.

References

1. ^ ^{a b} Jonas DA, Elmadfa I, Engel KH, et al. (2001). "Safety considerations of DNA in food". Ann Nutr Metab. 45 (6): 235–54. PMID 11786646. http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=anm45235. 
2. ^ Wurtman RJ, Regan M, Ulus I, Yu L (Oct 2000). "Effect of oral CDP-choline on plasma choline and uridine levels in humans". Biochem Pharmacol. 60 (7): 989–92. PMID 10974208. http://linkinghub.elsevier.com/retrieve/pii/S0006-2952(00)00436-6. 

v • d • e Nucleobases, nucleosides, and nucleotides Nucleobases Purine (Adenine, Guanine, Purine analogue) · Pyrimidine (Uracil, Thymine, Cytosine, Pyrimidine analogue) Nucleosides/ (NB+pentose) Ribonucleosides Adenosine · Guanosine · Uridine · Cytidine Deoxyribonucleosides Deoxyadenosine · Deoxyguanosine · Thymidine · Deoxyuridine · Deoxycytidine Nucleotides/ (NS+phosphate) Ribonucleotide monophosphates (AMP, GMP, UMP, CMP) · diphosphates (ADP, GDP, UDP, CDP) · triphosphates (ATP, GTP, UTP, CTP) Deoxyribonucleotides monophosphates (dAMP, dGMP, dUMP, TMP, dCMP) · diphosphates (dADP, dGDP, TDP, dCDP) · triphosphates (dATP, dGTP, TTP, dCTP) Cyclic cAMP, cGMP, c-di-GMP, cADPR Major families of biochemicals Saccharides/Carbohydrates/Glycosides · Amino acids/Peptides/Proteins/Glycoproteins · Lipids/Terpenes/Steroids/Carotenoids · Alkaloids/Nucleobases/Nucleic acids · Cofactors/ Flavonoids/Polyketides/Tetrapyrroles

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