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See "What is the depletion of the ozone layer?"
on forward biasing width of the depletion layer decreases whereas on reverse biasing the width of depletion layer increases.
Depletion layer is thin now. It is called depletion when the concentration is below 380 Dobson Units.
Ozone layer depletion has no significance. It is a deadly phenomenon.
Ozone layer depletion is the depletion of ozone. It has very bad affect on environment,