dermis

(dûr'mĭs)

[New Latin, back-formation from Late Latin epidermis, epidermis. See epidermis.]

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Deep layer of the skin, beneath the epidermis, containing blood vessels, muscles, nerve endings, and dense irregular connective tissue.

The corium; the principal layer of skin between the epidermis and the subcutaneous tissue; made up mostly of a network of collagen fibers but also containing nerves, blood vessels, cells and other fibers. It is divided into papillary and reticular parts, and when tanned forms leather.

• hoof d. — a greatly modified dermis, continuous at the coronet with the common dermis of the skin; the modified dermis supports the horn of the hoof.

The layer of skin just below the epidermis consisting of vascular connective tissue.

Normal skin anatomy. (Jarvis, 2000)

• Tissue, Fiber, and Integumentary System - dermis: inside layer of skin cells, providing elastic strength

This article is about the layer of skin. For the website, see DermIS (Dermatology Information System).

Dermis
Latin	dermis; corium
Code	TH H3.12.00.1.03001

A graphic representation of the interface between skin epithelium and the underlying connective tissue. Zone B, indicating the region of overlapping projections of epithelium and connective tissue, is the papillary dermis. Zone C, indicating the region of dermis that lies immediately subjacent to the interdigitations of epithelium, is the reticular dermis.

The dermis is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis.^[1] Structural components of the dermis are collagen, elastic fibers, and extrafibrillar matrix (previously called ground substance).^[2]

Contents 1 Components of the Dermis 2 Stratum papillare 3 Stratum reticulare 4 Additional images 5 See also 6 References

Components of the Dermis

The dermis is composed of three major types of cells^[3]: Fibroblasts, Macrophages, and Adipocytes.

Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and glycosaminoglycans^[3].

Stratum papillare

The stratum papillare sends conical elevations (papillae) into the epidermis which contain either terminal networks of blood capillaries or tactile Meissner's corpuscles. ^[4]

Stratum reticulare

The stratum reticulare possesses coarser and more regularly arranged collagenous fiber bundles.

Additional images

• 

  Epidermis and dermis of human skin.

• 

  Cross-section of all human skin layers.

See also

• Dermal papillae

References

1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. Pages 1, 11–12. ISBN 0-7216-2921-0.
2. ^ Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 8–9. ISBN 1-4160-3185-5.
3. ^ ^{a b} The Ageing Skin - Structure
4. ^ http://microvet.arizona.edu/Courses/vsc422/secure/VSC422AppledHistologyLabHandout.pdf

This dermatology article is a stub. You can help Wikipedia by expanding it. v d e

v d e Integumentary system (TA A16, TH H3.12, GA 10.1062) Skin Epidermis Stratum corneum · Stratum lucidum · Stratum granulosum · Stratum spinosum · Stratum basale Basement membrane zone Basal keratinocyte · Lamina lucida · Lamina densa Skin fields Head campus frontalis, campus parietalis, campus occipitalis, campus temroralis, campus facialis (campus orbitalis, campus nasalis, campus oralis, campus mentalis, campus infraorbitalis, campus buccalis, campus zygomaticus) Neck campus cervicalis anterior (campus submandibularis, campus caroticus, campus omotrachealis, campus submentalis), campus sternocleidomastoideus, campus cervicalis posterior (campus omoclavicularis), campus nuchalis Chest campus presternalis, campus clavipectoralis, campus pectoralis verus, campus mammarius, campus inframammarius, campus axillaris Abdomen campus hypochondriacus, campus epigastricus, campus abdominalis lateralis, campus umbilicalis, campus inguinalis, campus hypogastricus Perineum campus analis, campus urogenitalis Subcutaneous tissue Panniculus/Pannus (Panniculus adiposus · Panniculus carnosus) · Stratum membranosum · Loose connective tissue · Superficial fascia Adnexa Skin glands Sweat glands: Apocrine sweat gland · Eccrine sweat gland Sebaceous Hair Root sheath Outer root sheath · Inner root sheath (Henle's layer, Huxley's layer) Hair shaft Cuticle · Cortex · Medulla · Bulb with matrix cells · Hair follicle Muscle Arrector pili muscle Pilosebaceous unit Hair sebaceous gland Nail Nail matrix · Nail plate (Lunula)  · Eponychium · Paronychium · Hyponychium M: INT, SF, LCT anat/phys/devp noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon proc, drug (D2/3/4/5/8/11) M: SKA anat/phys/devp noco/cong/tumr, sysi/epon proc, drug(D10)

v d e Histology: connective tissue (TH H2.00.03) Composition Cells Resident Fibroblast · Fibrocyte · Reticular cell · Tendon cell Adipocyte Melanocyte Wandering cell Mast cell · Macrophage Extracellular matrix (noncellular) Ground substance Tissue fluid Fibers Collagen fibers Reticular fibers: COL3A1 Elastic fibers: Elastin · Fibrillin (FBN1, FBN2, FBN3) · EMILIN1 Elaunin Classification Connective tissue proper Loose Reticular · Adipose (Brown, White) Dense Dense irregular connective tissue (Submucosa, Dermis) · Dense regular connective tissue (Ligament, Tendon, Aponeurosis) Embryonic Mucoid · Mesenchymal Specialized Cartilage · Bone Related Soft tissue see also Template:Soft tissue tumors and sarcomas M: INT, SF, LCT anat/phys/devp noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon proc, drug (D2/3/4/5/8/11) M: MUS, DF+DRCT anat (h/n, u, t/d, a/p, l)/phys/devp/hist noco(m, s, c)/cong(d)/tumr, sysi/epon, injr proc, drug (M1A/3)

v d e Routes of administration / Dosage forms Oral Digestive tract (enteral) Solids Pill Tablet Capsule Time release technology Osmotic controlled release capsule (OROS) Liquids Solution Softgel Suspension Emulsion Syrup Elixir Tincture Hydrogel Buccal / Sublabial / Sublingual Solids Orally Disintegrating Tablet (ODT) Film Lollipop Lozenges Chewing gum Liquids Mouthwash Toothpaste Ointment Oral spray Respiratory tract Solids Smoking device Dry Powder Inhaler (DPI) Liquids pressurized Metered Dose Inhaler (pMDI) Nebulizer Vaporizer Gas Oxygen mask Oxygen concentrator Anaesthetic machine Relative analgesia machine Ocular / Otologic / Nasal Nasal spray Ear drops Eye drops Ointment Hydrogel Nanosphere suspension Mucoadhesive microdisc (microsphere tablet) Urogenital Ointment Pessary (vaginal suppository) Vaginal ring Vaginal douche Intrauterine device (IUD) Extra-amniotic infusion Intravesical infusion Rectal (enteral) Ointment Suppository Enema (Solution • Hydrogel) Murphy drip Nutrient enema Dermal Ointment Liniment Paste Film Hydrogel Liposomes Transfersome vesicals Cream Lotion Lip balm Medicated shampoo Dermal patch Transdermal patch Transdermal spray Jet injector Injection / Infusion (into tissue/blood) Skin Intradermal Subcutaneous Transdermal implant Organs Intracavernous Intravitreal Intra-articular or intrasynovial injection Transscleral Central nervous system Intracerebral Intrathecal Epidural Circulatory / Musculoskeletal Intravenous Intracardiac Intramuscular Intraosseous Intraperitoneal Nanocell injection Additional explanation: Mucous membranes are used by the human body to absorb the dosage for all routes of administration, except for "Dermal" and "Injection/Infusion". Administration routes can also be grouped as Topical (local effect) or Systemic (defined as Enteral = Digestive tract/Rectal, or Parenteral = All other routes).

v d e Routes of administration by organ system Gastrointestinal Oral • Buccal • Sublabial • Sublingual • Rectal Respiratory system Pulmonary • Nasal Visual system / Auditory system Ocular (Ocular-topical / Intravitreal / Transscleral) • Otologic (Oto-topical) Reproductive system Intracavernous • Intravaginal • Intrauterine (Extra-amniotic) Urinary system Intravesical Peritoneum Intraperitoneal Central nervous system Intracerebral • Intrathecal • Epidural Circulatory system Intravenous • Intracardiac Musculoskeletal system Intramuscular • Intraosseous Skin Epicutaneous • Intradermal • Subcutaneous

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Dansk (Danish)
n. - huden, læderhuden

Nederlands (Dutch)
(onder)huid

Français (French)
n. - hypoderme, derme

Deutsch (German)
n. - Haut, Unterhaut

Ελληνική (Greek)
n. - (ανατ.) χόριο

Italiano (Italian)
derma

Português (Portuguese)
n. - derme (f), pele (m)

Русский (Russian)
дерма

Español (Spanish)
n. - dermis

Svenska (Swedish)
n. - skinn (med.)

中文（简体）(Chinese (Simplified))
真皮, 皮肤

中文（繁體）(Chinese (Traditional))
n. - 真皮, 皮膚

한국어 (Korean)
n. - 진피

日本語 (Japanese)
n. - 真皮, 皮膚

العربيه (Arabic)
‏(الاسم) الأدمه ( باطن الجلد تحت البشرة)‏

עברית (Hebrew)
n. - ‮עור‬

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