The first gene causing lissencephaly, LIS1, was identified in patients with Miller-Dieker syndrome, a genetic syndrome caused by deletions of chromosome 17 that is a combination of lissencephaly and other facial deformities

The list of signs and symptoms mentioned in various sources for Miller-Dieker syndrome includes the 37 symptoms listed below: * Failure to thrive * Feeding problems * Limited developmental skills * Incomplete brain development * Smooth brain surface * Pachygyria * Heterotopias * Failure of opercula to develop * Absent corpus callosum * Hypoplastic corpus callosum * Large cavum septi pellucidi * Severe mental deficiency * Reduced muscle tone * Opisthotonos * Spasticity * Failure to thrive * Seizures * Hypsarrhythmia * Small head * Bitemporal narrowing * High forehead * Central forehead ridging * Central forehead furrowing * Small nose * Anteverted nostrils * Up-slant to palpebral fissures * Protuberant upper lip * Small lower jaw * Low-set auricles * Posteriorly angulated auricles * Wide secondary alveolar ridge * Late eruption of primary teeth * Undescended testes * Pilonidal sinus * Fifth finger clinodactyly * Transverse palmar crease * Polyhydramnios Note that Miller-Dieker syndrome symptoms usually refers to various symptoms known to a patient, but the phrase Miller-Dieker syndrome signs may refer to those signs only noticable by a doctor.

The cast of The Olin Experience - 2005 includes: Sarah Boman as herself Thomas Cecil as himself Michael Crayton as himself Brittany Devlin as herself Dean Dieker as himself Anita Kalra as herself Robin Maslowski as herself Jeffrey Satwicz as himself Tiana Veldwisch as herself David Wurtz as himself

The cast of The Finest Hour - 1992 includes: Erik Degn as Thurston Daniel Dieker as Albie Baruch Dror as Greenspan Michael Fountain as Carter Uri Gavriel as Commander Tracy Griffith as Barbara Ava Haddad as Nurse Isabel Gale Hansen as Dean Mazzoli Jonathan Herson Evyatar Lazar as Moonjean Eb Lottimer as Bosco Rob Lowe as Lawrence Hammer Stephen Sherman as General Gilya Stern as Diane Gregory Tal as Big Soldier Jack Widerker as Taylor

The cast of Doppelsterne - 2003 includes: Isabella Ballwein as Theresia at 8 Orlando Barbaro as Padre Sandra Brando Andreas Constantine as Father in Hospital Markus Dieker as Courier Lehmert Dominik as Johann at 14 Peter Eckl as Andreas von Baumgartner Karl Forcher as Henninger Werner Friedl Christoph Fuisting as Benedictine Monk Clemens Gehrlich as Son Ludwig Doppler at 14 Francesco Gonella as Dottore Pietans Johann Haberl as Professor Hantschl Christian Haslecker as Franz Exner Thomas Hochrathner as Colleague in the Factory Markus Humer as Christian Doppler as a baby Matthias Husinsky as Daguerrotypist Melitta Ilich as Landlady Madeleine Jobst as Anna at 2 Peter Jungbauer as Governor Patrick Juriga as Child Christian at 5 Dietmar Juriga as Johann Doppler Sarah Juriga as Katharina at 10 Wolfgang Karl as Judge Roland Keil as Karl Kreil Gunter Ladurner as Neurologist Johann Mayr as Chairman Peter Mittermayr as Bernard Bolzano Herbert Moser as Librarian Gerhard Oberauer as Servant Christine Oberhammer as Mother in Hospital Manfred Oberngruber as Minister Thun-Hohenstein Ursula Oberweger as Midwife Hans Ospald as Professor Polytechnic Institute Sara Padovani as Antonia Martin Pimmingstorfer as Postman Franz Presl as Principal of the Polytechnic Institute Alexandra Schimak as Mother in Hospital Philipp Sonnleitner as Anton Stampfer Georg Steinitz as Professor 2 Clara Strasser as Daughter Berta Doppler at 8 Andreas Strasser as Karel Koristka Wiltraud Straub as Mother of Christian Karoline Tatzreiter as Daughter Mathilde Doppler at 15 Albert Tatzreiter as Son Hermann Doppler at 6 Volker Wahl Franz Walter Schett as Factory Owner Johann Winkler as Christian Andreas Doppler Clemens Wolfgang Stiedl as Gregor Mendl