Yes. Dimethyl sulfoxide is dangerous. It is a polar aprotic
solvent and can transport compounds through the skin and body
extremely well. It is an industrial chemical, and not approved for
use on humans by the f.d.a. If you are going to use it topically,
dilute it a lot and use with something like aloe vera, vit c, tart
cherry juice, activated silica, or some antioxidant because
dimethyl sulfoxide is an oxidant. Only use on extremely clean skin
because any crap on there will get dissolved into bloodstream,
muscle, fat, who knows - maybe even bone.