Let's start off with stating that any and all substances can kill you (even too much water), whether they be legal or not. Since you ask which illegal drugs can kill you, the answer would be ALL illegal drugs. The following is an attempt list of all controlled substances:

((+/-)cis-4,5-dihydro-4-methyl-5-phenyl-2-oxazolamine)

(+/-)cis-4-methylaminorex

1-[1-(2-thienyl)cyclohexyl]

1-phenylcyclohexylamine

1-piperidinocyclohexanecarbonitrile

2,5-dimethoxy-4-ethylamphet-amine

3,4,5-trimethoxy

3,4-methylenedioxy-N-ethylamphetamine

3,4-methylenedioxymethamphetamine

3-Methylfentanyl

3-methylthiofentanyl

4-Bromo-2,5-dimethoxyphenethylamine

4-methoxyamphetamine

4-methyl-2,5-dimethoxy-amphetamine

Acetorphine

Acetyl-alpha-methylfentanyl

Acetyldihydrocodeine

Acetylmethadol

Alfentanil

Allylprodine

Alpha-ethyltryptamine

Alpha-methylfentanyl

Alpha-methylthiofentanyl

Alpha-methyltryptamine

Alphacetylmethadol

Alphameprodine

Alphamethadol

Alphaprodine

Amobarbital

Amphetamine

Anabolic

Anileridine

Benzethidine

Benzphetamine

Benzylmorphine

Beta-hydroxy-3-methylfentanyl

Beta-hydroxyfentanyl

Betacetylmethadol

Betameprodine

Betamethadol

Betaprodine

Bezitramide

Bufotenine

Carfentanil

Cathinone

Chlorhexadol

Chlorphentermine

Clonitazene

Clortermine

Cocaine

Codeine

Codeine-N-Oxide

Cyprenorphine

Desomorphine

Dextromoramide

Diampromide

Diethylthiambutene

Difenoxin

Dihydrocodeine

Dihydroetorphine

Dihydromorphine

Dimenoxadol

Dimepheptanol

Dimethylthiambutene

Dimethyltryptamine

Dioxaphetyl

Diphenoxylate

Dipipanone

Dronabinol

Drotebanol

Ethylamine

Ethylmethylthiambutene

Ethylmorphine

Etonitazene

Etorphine

Etoxeridine

Fentanyl

Furethidine

Glutethimide

Granulated

Heroin

Hydrocodone

Hydromorphinol

Hydromorphone

Hydroxypethidine

Ibogaine

Isomethadone

Ketamine,

Ketobemidone

Levo-alphacetylmethadol

Levomoramide

Levophenacylmorphan

Levorphanol

Lysergic

MPPP

Marihuana

Mecloqualone

Mescaline

Metazocine

Methadone

Methadone-Intermediate

Methamphetamine

Methaqualone

Methcathinone

Methylaminorex

Methyldesorphine

Methyldihydromorphine

Methylphenidate

Methyprylon

Metopon

Moramide-Intermediate

Morpheridine

Morphine

Morphine-N-Oxide

Myrophine

N,N-dimethylamphetamine

N-Benzylpiperazine

N-[1-(2-thienyl)methyl-4-piperidyl]-N-phenylpropanamide

N-[1-benzyl-4-piperidyl]-N-phenylpropanamide

N-ethyl-3-piperidyl

N-ethylamphetamine

N-hydroxy-3,4-methylenedioxyamphetamine

N-methyl-3-piperidyl

Nabilone

Nicocodeine

Nicomorphine

Noracymethadol

Norlevorphanol

Normethadone

Normorphine

Norpipanone

Opium

Oxycodone

Oxymorphone

PEPAP

Para-fluorofentanyl

Parahexyl

Pentobarbital

Pethidine

Pethidine-Intermediate-A

Pethidine-Intermediate-B

Pethidine-Intermediate-C

Phenadoxone

Phenampromide

Phenazocine

Phencyclidine

Phendimetrazine

Phenmetrazine

Phenomorphan

Phenoperidine

Pholcodine

Piminodine

Piritramide

Powdered

Proheptazine

Properidine

Propiram

Psilocybin

Psilocyn

Pyrrolidine

Racemethorphan

Racemoramide

Racemorphan

Remifentanil

Secobarbital

Sufentanil

Sulfondiethylmethane

Sulfonethylmethan

Sulfonmethane

Tetrahydrocannabinols

Thebacon

Thebaine

Thiofentanyl

Thiophene

Tiletamine

Tilidine

Tincture

Trimeperidine

gamma hydroxybutrate

gamma-hydroxybutyric acid

How will they kill you? Given the exhausting list, the simplest way to answer that is by overdose. Obviously, a drug overdose is unique to the drug that's causing it. Instead of listing each drug's mechanism of overdose here, I recommend you find the drug you're interested in and then look up info on it, including things like its LD50.

There no known fatal dose of LSD.Cannabis youd have to take so much youd be sick before you OD'd.Theres never been a recorded case of LSD or cannabis overdose.

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