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Mr. and Mrs. Quagmire did die. Isadora and Duncan were taken by The Great Unknown and it is not known whether they survived.
There are Duncan,Isadora and Quigley
Well he became good friends with Isadora Quagmire and Duncan Quagmire at Prutfrock Prep but he is very close to his sisters, Violet and Sunny
Isadora Duncan's birth name is Angela Isadora Duncan.
Isadora Duncan is 5' 6".