Earl Wilbur Sutherland, Jr.
| Columbia Encyclopedia: Earl Wilbur Sutherland |
Sutherland, Earl Wilbur, 1915–1974, American pharmacologist and physiologist, b. Burlingame, Kans., M.D., Washington Univ. Medical School, 1942. He was a professor at Washington Univ. (1945–53), at Western Reserve Univ. (now Case Western Reserve Univ., 1953–63), and at Vanderbilt Univ. (1963–74). Sutherland won the 1971 Nobel Prize in physiology or medicine for elucidating the behavior of hormones at the cellular level. He isolated cyclic adenosine monophosphate (cyclic AMP) and demonstrated its involvement in various metabolic processes. His work paved the way for later research on cell signaling and gene expression.
| Medical Dictionary: Suth·er·land |
(sŭTH'ər-lənd), Earl Wilbur, Jr 1915–1974.
American physiologist. He won a 1971 Nobel Prize for showing that cyclic AMP within the cell is the agent that moderates the action of hormones.
| Wikipedia: Earl Wilbur Sutherland, Jr. |
| Earl Wilbur Sutherland, Jr. | |
 Earl Wilbur Sutherland, Jr.
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| Born | November 19, 1915 Burlingame, Kansas |
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| Died | March 9, 1974 Miami, Florida |
| Nationality | American |
| Fields | biochemistry |
| Institutions | Vanderbilt University |
| Alma mater | Washburn University |
| Known for | epinephrine |
| Notable awards | Nobel Prize in Physiology or Medicine in 1971 |
Earl Wilbur Sutherland Jr. (November 19, 1915 – March 9, 1974) was an American pharmacologist and biochemist. Sutherland was born in Burlingame, Kansas. He won a Nobel Prize in Physiology or Medicine in 1971 "for his discoveries concerning the mechanisms of the action of hormones," especially epinephrine, via second messengers (such as cyclic adenosine monophosphate, cyclic AMP).
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Career
Sutherland received his bachelor's degree in chemistry in 1937 from Washburn University, Topeka, Kansas and earned his medical degree in 1942 from Washington University School of Medicine in St. Louis. After serving as a doctor in World War II, he returned to Washington University as a researcher in the pharmacology laboratory of Nobel laureate Carl Ferdinand Cori. In 1953, he became director of the department of pharmacology at Case Western Reserve University (then Western Reserve University) in Cleveland, Ohio, where he discovered the role of cyclic AMP in mediating the action of certain hormones. In 1963, desiring to limit his duties to research, Sutherland moved to Vanderbilt University School of Medicine in Nashville, where he was a professor of physiology until 1973. At the time of his death in 1974, Sutherland was a distinguished professor of biochemistry at University of Miami Medical School.
Awards and honours
In addition to the Nobel Prize of 1971, Sutherland won the Albert Lasker Award for basic medical research in 1970, and received the National Medal of Science in 1973. He was elected to the National Academy of Sciences in 1966. A residential dormitory at Vanderbilt was named in Sutherland's honor, and a plaque and photographic display there commemorate his achievements.
References
- Shampo, M A; Kyle R A (June 2000). "Earl Sutherland--Nobel Prize for Hormone Research". Mayo Clin. Proc. (UNITED STATES) 75 (6): 552. ISSN 0025-6196. PMID 10852412.
- Raju, T N (September 1999). "The Nobel chronicles. 1971: Earl Wilbur Sutherland, Jr. (1915-74)". Lancet (ENGLAND) 354 (9182): 961. ISSN 0140-6736. PMID 10489991.
- Butcher, R W; Robison G A (March 1975). "An appreciation of Earl Sutherland". Metab. Clin. Exp. (UNITED STATES) 24 (3): 237–40. doi:. PMID 1092953.
- Ho, R J; Russell T, Asakawa T (March 1975). "The last conversation with Dr. Earl W. Sutherland, Jr: the feedback regulation of cyclic nucleotides". Metab. Clin. Exp. (UNITED STATES) 24 (3): 257–64. doi:. PMID 165349.
- "Dr. Sutherland, AHA career investigator, dies in Miami". Circ. Res. (UNITED STATES) 34 (5): 743. May. 1974. ISSN 0009-7330. PMID 4597081.
- Oye, I (November 1971). "[The Nobel Prize in Medicine to Earl W. Sutherland Jr]". Tidsskr. Nor. Laegeforen. (NORWAY) 91 (31): 2270–1. ISSN 0029-2001. PMID 4332258.
- "[Nobel prize for Medicine and Physiology 1972]". Münchener medizinische Wochenschrift (1950) (GERMANY, WEST) 113 (45): Suppl 45:1. November 1971. ISSN 0027-2973. PMID 4942165.
- Kampmeier, R H (November 1971). "Cycl AMP--and the Nobel Prize". South. Med. J. (UNITED STATES) 64 (11): 1413–4. ISSN 0038-4348. PMID 4331313.
- "[Nobel prize for medicine 1971]". Dtsch. Med. Wochenschr. (GERMANY, WEST) 96 (44): 1735. October 1971. ISSN 0012-0472. PMID 4939258.
- "Nobel prize". Br Med J (ENGLAND) 4 (5781): 188. October 1971. ISSN 0007-1447. PMID 4329929.
- "1971 Nobel Prize for physiology and medicine". Triangle; the Sandoz journal of medical science (SWITZERLAND) 10 (4): 173–4. 1971. ISSN 0041-2597. PMID 4337412.
- Ishikawa, E (April 1969). "[Profile of Professor Earl W. Sutherland Jr]". Nippon Rinsho (JAPAN) 27 (4): 1301–4. ISSN 0047-1852. PMID 4896683.
External links
- Nobel link
- Nobel archive link
- Lasker link
- NAS link
- Case-Western link
- Earl Sutherland profile at NNDB
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Mentioned in
- Year 1956 (in Science & Technology)
- Sutherland (disambiguation)
- List of Washburn University alumni
- Burlingame, Kansas
- Earl (given name)
- List of Nobel laureates affiliated with Washington University in St. Louis
- March 9
- November 19
- 1915
- List of people from Kansas
- List of Nobel laureates
- 1974
- List of Nobel laureates by university affiliation
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