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echinacea

 

Definition

Echinacea, or purple coneflower, is a perennial herb of the Composite family, commonly known as the daisy family. Most often referred to as the purple coneflower, this hardy plant also known as Sampson root, Missouri snakeroot, and rudbeckia. The prominent, bristly seed head inspired the generic name of the plant, taken from the Greek word echinos meaning hedgehog.

Description

Echinacea is a North American prairie native, abundant in the Midwest, and cultivated widely in ornamental and medicinal gardens. The purple-pink rays of the blossom droop downward from a brassy hued center cone composed of many small, tubular florets. The conspicuous flowers bloom singly on stout, prickly stems from mid-summer to autumn. Flower heads may grow to 4 in (10.16 cm) across. The dark green leaves are opposite, entire, lanceolate, toothed, and hairy with three prominent veins. The narrow upper leaves are attached to the stem with stalks. The lower leaves are longer, emerging from the stem without a leaf stalk, and growing to 8 in (20.32 cm) in length. The plant develops deep, slender, black roots. Echinacea propagates easily from seed or by root cuttings. However, due to its increasing popularity as an herbal supplement, echinacea is numbered among the 19 medicinal plants considered at risk by the Vermont nonprofit organization, United Plant Savers.

— Clare Hanrahan



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Dictionary: ech·i·na·ce·a   (ĕk'ə-nā'sē-ə, -nā'shə) pronunciation
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n.
  1. Any of several coneflowers of the genus Echinacea, having usually pinkish-purple ray flowers.
  2. The roots, seeds, or other parts of such a plant, used in herbal medicine.

[New Latin Echīnācea, genus name, from Latin echīnus, sea urchin (from its rough leaves). See echinus.]


Sci-Tech Encyclopedia: Echinacea
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A superorder of Euechinoidea, having a rigid test, the periproct within the apical system, keeled teeth, a complete perignathic girdle, and branchial slits. J. Durham and R. Melville (1957) include five orders in this group. These were formerly distributed among the Stirodonta and Camarodonta in the classification of R. Jackson (1912). See also Echinodermata; Echinoida; Euechinoidea; Hemicidaroida; Phymosomatoida; Salenioida.


Drug Info: Echinacea
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Brand names: Centrum® Herbals Echinacea, Echinaforce®, Echinafresh®, Echinaguard®, Esberitox™, One-A-Day® Cold Season, ViraMedx®



Echinacea skin ointment

What is echinacea skin ointment?

ECHINACEA skin ointment (ViraMedx® Ointment) is a topical herbal remedy available for non-prescription use. This skin ointment is promoted for treating cold sores, which are caused by one of the herpes viruses. The echinacea mixture acts as an antiseptic and inhibits (but does not kill) the virus. In addition to echinacea, the ointment also contains a drug called pramoxine, which is a mild local anesthetic used as a pain reliever. Medical study to date does not support using echinacea skin ointment for any other purpose other than for cold sores.

What should I tell my health care provider before I take this medicine?

It is important for you to tell your prescriber or other health care professional that you are using echinacea. Some herbs exert potent effects and may interact with other drugs you are taking.

You should discuss echinacea skin ointment with your health care professional BEFORE using it if you have any of these conditions:
• an autoimmune disorder, like lupus
• an immunodeficiency syndrome like HIV-virus infection or AIDS
• cancer
• chronic lung diseases, like asthma, emphysema, or bronchitis
• diabetes or high blood sugar
• kidney or liver disease
• multiple sclerosis or other chronic neurological disease
• organ transplant
• rheumatoid arthritis
• tuberculosis
• an unusual or allergic reaction to Echinacea, other herbs or plants, pramoxine or other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

This ointment is applied to the skin of the affected area several times per day. For external use only. Follow the directions on the package labeling, or talk to your health care professional for instructions on using. This ointment is most effective if you start applying it at the first sign of a cold sore.

Echinacea skin ointment should not be used for longer than 7 days without the advice of a health care professional. A potential problem with self-treatment could be delay in detection of a serious skin problem.

Contact your pediatrician or health care professional regarding the use of this herb in children. Special care may be needed.

What if I miss a dose?

Missing a dose is probably not harmful. If you miss a dose, simply resume applying the ointment as soon as you remember.

What drug(s) may interact with echinacea?

Drug interactions with this skin ointment are not likely; however, if you are using other medicated creams or ointments, check with your health care professional. You may need to separate the times of application to the skin.

For many herbs, interactions with other medications are unknown. That is why you should always be careful when mixing herbal remedies with traditional medications. If you take any other medications, consult with your health care professional prior to taking echinacea.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking echinacea?

Since echinacea is derived from a plant, allergic reactions are possible. Stop using this ointment if you develop a rash or an allergic-type reaction. You may need to inform your health care professional this has occurred.

If your condition has not improved in 7 days or has worsened, contact your prescriber. This ointment is not intended for longer use without the supervision of a health care professional.

If you are scheduled to have surgery or dental work, remember to tell your dentist, surgeon and anesthesia specialist that you are using echinacea. In some cases they may want you to discontinue using the product prior to the surgery.

What side effects may I notice from using echinacea?

Side effects that you should report to your prescriber or health care professional as soon as possible:
• skin rash or itching

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature; do not freeze. Throw away any unused ointment after the expiration date.


Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

Description

Echinacea, commonly known as the purple coneflower, is a perennial herb of the Composite family, commonly known as the daisy family. Most often referred to as the purple coneflower, this hardy plant is also known as Sampson root, Missouri snakeroot, and rudbeckia. The prominent, bristly seed head inspired the generic name of the plant, taken from the Greek word, echinos meaning hedgehog.

Echinacea is a North American prairie native, abundant in the mid west and cultivated widely in ornamental and medicinal gardens. The purple-pink rays of the blossom droop downward from a brassy hued center cone composed of many small, tubular florets. The conspicuous flowers bloom singly on stout, prickly stems from mid-summer to autumn. Flower heads may grow to 4 in (10.16 cm) across. The dark green leaves are opposite, entire, lanceolate, toothed, and hairy with three prominent veins. The narrow upper leaves are attached to the stem with stalks. The lower leaves are longer, emerging from the stem without a leaf stalk, and growing to 8 in (20.32 cm) in length. The plant develops deep, slender, black roots. Echinacea propagates easily from seed or by root cuttings. However, due to its increasing popularity as an herbal supplement, echinacea is numbered among the 19 medicinal plants considered at risk by the Vermont nonprofit organization United Plant Savers.

General Use

Three species of echinacea are useful medicinally: Echinacea augustifolia, Echinacea purpurea, and Echinacea pallida. The entire plant has numerous medicinal properties that act synergistically to good effect. Echinacea is most often used to boost the immune system and fight infection. Research has shown that echinacea increases production of interferon in the body. It is antiseptic and antimicrobial, with properties that act to increase the number of white blood cells available to destroy bacteria and slow the spread of infection. As a depurative, the herbal extract cleanses and purifies the bloodstream, and has been used effectively to treat boils. Echinacea is vulnerary, promoting wound healing through the action of a chemical substance in the root known as caffeic acid glycoside. As an alterative and an immuno-modulator, echinacea acts gradually to promote beneficial change in the entire system. It has also been used to treat urinary infection and Candida albicansinfections. Echinacea is a febrifuge, useful in reducing fevers. It is also useful in the treatment of hemorrhoids. A tincture, or a strong decoction of echinacea serves as an effective mouthwash for the treatment of pyorrhea and gingivitis.

Native American plains Indians relied on echinacea as an all-purpose antiseptic. The Sioux tribe valued the root as a remedy for snake bite, the Cheyenne tribe chewed the root to quench thirst, and another tribe washed their hands in a decoction of echinacea to increase their tolerance of heat. European settlers learned of the North American herb's many uses, and soon numerous echinacea-based remedies were commercially available from pharmaceutical companies in the United States. Echinacea was a popular remedy in the United

States through the 1930s. It was among many medicinal herbs listed in the U.S. Pharmacopoeia, the official U.S. government listing of pharmaceutical raw materials and recipes. The herb fell out of popular use in the United States with the availability of antibiotics. In West Germany, more than 200 preparations are made from the species E. purpurea. Commercially prepared salves, tinctures, teas, and extracts are marketed using standardized extracts. Echinacea is regaining its status in the United States as a household medicine-chest staple in many homes. It is one of the best-selling herbal supplements in U.S. health food stores.

Clinical studies have found that the entire plant possesses medicinal properties with varying levels of effectiveness. Echinacea is of particular benefit in the treatment of upper respiratory tract infections. Some research has shown that echinacea activates the macrophages that destroy cancer cells and pathogens. When taken after cancer treatments, an extract of the root has been found to increase the body's production of white blood cells. Echinacea has been shown to be most effective when taken at the first sign of illness, rather than when used as a daily preventative. Other research has demonstrated the significant effect of E. purpurea root on reducing the duration and severity of colds and flu. Some herbal references list only the root as the medicinal part, others include the aerial parts of the plant, particularly the leaf. Most research has been done on the species E. pallida and E. purpurea. All three species of echinacea are rich in vitamins and minerals. Echinacea is an herbal source of niacin, chromium, iron, manganese, selenium, silicon, and zinc.

While echinacea has proven effective for treating or preventing upper respiratory tract infections, scientific research proving its effectiveness for other uses still lacks, according to a report released in early 2002. The report says that data for other uses of the herb are inconclusive or don't exist.

Preparations

The quality of any herbal supplement depends greatly on the conditions of weather and soil where the herb was grown, the timing and care in harvesting, and the manner of preparation and storage.

Decoction is the best method to extract the mineral salts and other healing components from the coarser herb materials, such as the root, bark, and stems. It is prepared by adding 1 oz (0.028 kg) of the dried plant materials, or 2 oz (560 g) of fresh plant parts, to one pint of pure, unchlorinated, boiled water in a non-metallic pot. The mixture is simmered for about one half hour, then strained and covered. A decoction may be refrigerated for up to two days and retain its healing qualities.

An infusion is the method used to derive benefits from the leaves, flowers, and stems in the form of an herbal tea. Twice as much fresh, chopped herb as dried herb should be used. It is steeped in one pint of boiled, unchlorinated water for 10-15 minutes. Next, it is strained and covered. The infusion is drunk warm and sweetened with honey if desired. A standard dose is three cups per day. An infusion will keep for up to two days in the refrigerator and retain its healing qualities.

A tincture is the usual method to prepare a concentrated form of the herbal remedy. Tinctures, properly prepared and stored, will retain medicinal potency for two years or more. Combine 4 oz (112 g) of finely cut fresh or powdered dry herb with one pint of brandy, gin, or vodka, in a glass container. The alcohol should be enough to cover the plant parts and have a 50/50 ratio of alcohol to water. The mixture should be placed away from light for about two weeks and shaken several times each day. It should be strained and stored in a tightly capped, dark glass bottle. A standard dose is one 4 ml of the tincture three times a day.

Precautions

Echinacea is considered safe in recommended doses. Pregnant or lactating women, however, are advised not to take echinacea in injection form. Because the plant has proven immuno-modulating properties, individuals with systemic lupus erythmatosus, rheumatoid arthritis, tuberculosis, leukemia, multiple sclerosis, or AIDS should consult their physician before using echinacea. Echinacea should not be given to children under two years of age and it should only be given to children over two in consultation with a physician. Research indicates that echinacea is most effective when taken at first onset of symptoms of cold or flu, and when usage is continued no longer than eight weeks. There is some indication that the herb loses its effectiveness when used over a long period of time. It is necessary to interrupt use for a minimum of several weeks in order to give the body's immune system the opportunity to rest and adjust.

Side Effects

No side effects are reported with oral administration of echinacea, either in tincture, capsule, or as a tea, when taken according to recommended doses. Chills, fever, and allergic reactions have been reported in some research studies using an injection of the plant extract. Different brands of echinacea vary considerably in effectiveness.

Interactions

Those taking drugs to suppress the immune system should check with their doctors before taking Echinacea. When used in combination with other herbs, dosage should be lowered.

Resources

Books

Foster, Steven and James A. Duke. A Field Guide to Medicinal Plants. New York: The Peterson Field Guide Series, Houghton Mifflin Company, 1990.

Hoffmann, David. The New Holistic Herbal. Massachusetts: Element Books Inc., 1986.

Kowalchik, Claire and William H. Hylton, editors. Rodale's Illustrated Encyclopedia of Herbs. Pennsylvania: Rodale Press Inc., 1987.

McIntyre, Anne. The Medicinal Garden. Henry Holt and Company Inc., 1997.

Official Proceedings. Medicines from the Earth, Protocols for Botanical Healing. Massachusetts: Gaia Herbal Research Institute, 1996.

Ondra, Nancy, editor. "200 Herbal Remedies." Excerpted from The Complete Book of Natural & Medicinal Cures. Pennsylvania: Rodale Press Inc., 1994.

Weed, Susun S. Wise Woman Ways, Menopausal Years. New York: Ash Tree Publishing, 1992.

Periodicals

Deneen, Sally and Tracey C. Rembert. "Stalking Medicinal Plants, An International Trade Imperils Wild Herbs." E Magazine (July/August 1999).

Schardt, David and Barbara Sorkin. "Echinacea." Nutrition Action Newsletter 29, no. 2 (March 2002):1–6.

Wallace, Phil. "Popular Herbal Supplements Get Mixed Reviews in Journal." Food Chemical News (January 7, 2002):30.

Other

Herb World News Online, Research Reviews. http://www.herbs.org. Herb Research Foundation, 1999.

[Article by: Clare Hanrahan; Teresa G. Odle]


Any member of the coneflower genus Echinacea. Commonly called the purple coneflower, echinacea is used as a border plant. The leaves and roots are used in herbal remedies to boost the immune system and in the treatment of colds and flu.

For more information on echinacea, visit Britannica.com.

 
Columbia Encyclopedia: echinacea
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echinacea (ĕk'ənā'shēə), popular herbal remedy, or botanical, believed to benefit the immune system. It is used especially to alleviate common colds and the flu. Several controlled studies using it as a cold medicine have failed to find any benefit from its use, but a 2007 review of 14 different studies said that echinacea could have modest to marked effects against cold viruses. Echinacea is extracted from the roots and flowering tops of the purple coneflower (Echinacea angustifolia and E. purpurea).


Veterinary Dictionary: Echinacea
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A genus of plants in the family Astraceae; source of the popular herbal product echinacea, used mainly as a stimulant of the immune system.

Gardener's Dictionary: Echinacea
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The botanical name for purple coneflower.

echinacea

Wikipedia: Echinacea
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Echinacea
Echinacea purpurea 'Maxima'
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Asterales
Family: Asteraceae
Tribe: Heliantheae
Genus: Echinacea
Species

See text

Echinacea (pronounced /ˌɛkɨˈneɪʃ(iː)ə/),[1] is a genus of nine species of herbaceous plants in the family Asteraceae which are commonly called purple coneflowers. All are endemic to eastern and central North America, where they are found growing in moist to dry prairies and open wooded areas. They have large, showy heads of composite flowers, blooming from early to late summer. The genus name is from the Greek echino, meaning "spiny," due to the spiny central disk. Some species are used in herbal medicines and some are cultivated in gardens for their showy flowers. A few species are of conservation concern.

The spiny center of the head showing the paleae, from which the name derives

Contents

Description

Echinacea species are herbaceous, drought-tolerant perennial plants growing up to 140 cm in height. They grow from taproots, except E. purpurea, which grows from a short caudice with fibrous roots. They have erect stems that in most species are unbranched. Both the basal and cauline leaves are arranged alternately. The leaves are normally hairy with a rough texture, having uniseriate trichomes (1-4 rings of cells) but sometimes they lack hairs. The basal leaves and the lower stem leaves have petioles, and as the leaves progress up the stem the petioles often decrease in length. The leaf blades in different species may have one, three or five nerves. Some species have linear to lanceolate shaped leaves, and others have elliptic to ovate shaded leaves, often the leaves decrease in size as they progress up the stems. Leaf bases gradually increase in width away from the petioles or the bases are rounded to heart shaped. Most species have leaf margins that are entire, but sometimes they are dentate or serrate. The flowers are collected together into single, rounded Heads that terminate long peduncles. The inflorescences have crateriform to hemispheric shaped involucres which are 12–40 mm wide. The phyllaries, or bracts below the flower head, are persistent and number 15–50. The phyllaries are produced in 2–4 series. The receptacles are hemispheric to conic in shape. The paleae have orange to reddish purple ends, and are longer than the disc corollas. The paleae bases partially surrounding the cypselae, and are keeled with the apices abruptly constricted to awn-like tips. The ray florets number 8–21 and the corollas are dark purple to pale pink, white, or yellow. The tubes of the corolla are hairless or sparsely hairy, and the laminae are spreading, reflexed, or drooping in habit and linear to elliptic or obovate in shape. The abaxial faces of the laminae are glabrous or moderately hairy. The flower heads have typically 200-300 fertile, bisexual disc florets but some have more. The corollas are pinkish, greenish, reddish-purple or yellow and have tubes shorter than the throats. The pollen is normally yellow in most species, but usually white in E. pallida. The three or four-angled fruits, called cypselae, are tan or bicolored with a dark brown band distally. The pappi is persistent and variously crown-shaped with 0 to 4 or more prominent teeth. x = 11.[2]

Like all asteraceae, the flowering structure is a composite inflorescence, with purple (rarely yellow or white) florets arranged in a prominent, somewhat cone-shaped head — "cone-shaped" because the petals of the outer ray florets tend to point downward (are reflexed) once the flower head opens, thus forming a cone. Plants are generally long lived, with distinctive flowers. The common name "cone flower" comes from the characteristic center “cone” at the center of the flower. The genus name Echinacea is rooted in the Greek word "echinos", meaning hedge hog,[3] it references the spiky appearance and feel of the flower heads.

Species

A bee on an Echinacea paradoxa head (inflorescence)

The species of Echinacea are

Medicinal effects

One (in vitro) study suggested that some echinacea supplements could have some antitumor properties.[4] Marketed and studied medicinal products contain different species (E. purpurea, E. angustifolia, E. palida), different organs (roots and herbs) and different preparations (extracts and expressed juice). Their chemical composition is very different.[5][6] Despite this most reviews about medicinal effects of Echinacea do not discriminate between different products.[citation needed] A 2007 study by the University of Connecticut combined findings from 14 previously-reported trials examining Echinacea and concluded that Echinacea can cut the chances of catching a cold by more than half, and shorten the duration of a cold by an average of 1.4 days. However, Dr. Wallace Sampson, an editor of Scientific Review of Alternative Medicine and a Stanford University emeritus clinical professor of medicine, says that the referenced trials lack the similarities necessary to provide definitive results when combined into one report. “If you have studies that measure different things, there is no way to correct for that. These researchers tried, but you just can’t do it.”[7] 2003 A controlled double-blind study from the University of Virginia School of Medicine and documented in the New England Journal of Medicine[8] stated that echinacea extracts had "no clinically significant effects" on rates of infection or duration or intensity of symptoms. The effects held when the herb was taken immediately following infectious viral exposure and when taken as a prophylaxis starting a week prior to exposure. In a press release, Dr. Michael Murray, the Director of Education for Factors Group of Nutritional Companies, a manufacturer of Echinacea-related products, calls the study "faulty and inaccurate."[9] According to Dr. Murray, none of the three extracts used on the 399 study participants contained all three of the components of Echinacea responsible for its immune-enhancing effects: polysaccharides, alkylamides and cichoric acid. In addition, Dr. Murray said "the standard dosage for dried Echinacea angustifolia root is normally three grams per day or more and this study used less than one gram."

An earlier University of Maryland review based on 13 European studies concluded that echinacea, when taken at first sign of a cold, reduced cold symptoms or shortened their duration.[10] The review also found that three of four published studies concluded that taking echinacea to prevent a cold was ineffective.

The European Medicines Agency (EMEA) assessed[11] the body of evidence and approved the use of expressed juice and dried expressed juice from fresh flowering aerial parts of Echinacea purpurea for the short-term prevention and treatment of the common cold. According to their recommendations:

It should not be used for more than 10 days. The use in children below 1 year of age is contraindicated, because of theoretically possible undesirable effect on immature immune system. The use in children between 1 and 12 years of age is not recommended, because efficacy has not been sufficiently documented although specific risks are not documented. In the absence of sufficient data, the use in pregnancy and lactation is not recommended.[12]

Popular belief and traditional use

Echinacea is popularly believed to be an immunostimulator, stimulating the body's non-specific immune system and warding off infections. A study commonly used to support that belief is a 2007 meta-analysis in The Lancet Infectious Diseases.[13] The studies pooled in the meta-analysis used different types of echinacea, different parts of the plant, and various dosages. This review cannot inform recommendations on the efficacy of any particular type of echinacea, dosage, or treatment regimen. The safety of echinacea under long-term use is also unknown.[14]

History

Echinacea angustifolia was widely used by the North American Plains Indians for its general medicinal qualities.[15] Echinacea was one of the basic antimicrobial herbs of eclectic medicine from the mid 19th century through the early 20th century, and its use was documented for snakebite, anthrax, and for relief of pain. In the 1930s echinacea became popular in both Europe and America as a herbal medicine. According to Wallace Sampson, MD, its modern day use as a treatment for the common cold began when a Swiss herbal supplement maker was "erroneously told" that echinacea was used for cold prevention by Native American tribes who lived in the area of South Dakota.[7] Although Native American tribes didn't use echinacea to prevent the common cold, some of the tribes did use echinacea to treat some of the symptoms that could be caused by the common cold: The Kiowa used it for coughs and sore throats, the Cheyenne for sore throats, the Pawnee for headaches, and many tribes used it as an analgesic, including the Sioux from South Dakota.[16]

Native Americans learned of E. angustifolia by observing elk seeking out the plants and consuming them when sick or wounded, and identified those plants as elk root.[17]

Active substances

Like most crude drugs from plant or animal origin, the constituent base for echinacea is complex, consisting of a wide variety of chemicals of variable effect and potency. Some chemicals may be directly antimicrobial, while others may work at stimulating or modulating different parts of the immune system. All species have chemical compounds called phenols, which are common to many other plants. Both the phenol compounds cichoric and caftaric are present in E. purpurea, other phenols include echinacoside, which is found in greater levels within E. angustifolia and E. pallida roots than in other species. When making herbal remedies, these phenols can serve as markers for the quantity of raw echinacea in the product. Other chemical constituents that may be important in echinacea health effects include alkylamides and polysaccharides.

As with any herbal preparation, individual doses may vary significantly in active chemical composition. In addition to poor process control which may affect inter- and intra-batch homogeneity, species, plant part, extraction method, and contamination or adulteration with other products all lead to variability between products.[18][19]

Root or whole plant

As with any plant, the chemical makeup of echinacea is not consistent throughout the organism. In particular, the root has been promoted as containing a more efficacious mixture of active chemicals. A 2003 study in the Journal of the American Medical Association (Taylor et al. 2003[20]) found that when echinacea products made from the entire plant were taken after the second cold symptom appeared they provided no measurable beneficial effect for children in treating the severity or duration of symptoms caused by the common cold virus. The study has been criticized for using whole-plant extracts instead of root extracts, and the dosages studied were lower than those recommended by herbalists.[citation needed] A 2005 study in the New England Journal of Medicine (Turner, 2005[8]) focused on several root extracts, but still found no statistically significant effects on duration, intensity, or prevention of symptoms.

Frequency of administration

Proponents of echinacea assert that it is not a "one-dose" treatment, and that in order to work effectively, a dose should be taken at the very first sign of a cold symptom. Subsequent doses are called for every two to four hours after the first dose, including during the overnight sleeping period, until the cold symptoms have disappeared.[citation needed]

Species

The several species of echinacea differ in their precise chemical constitution, and may provide variable dosages of any active ingredients.

Side effects and contraindications

Reported adverse effects of echinacea are primarily allergic in nature also includes anaphylaxis, asthma attacks, thrombocytopenic purpura, leucopenia, abdominal pain, nausea, dysuria, arthralgia, myalgia, and dizziness.[21] These tend to be infrequent, mild, and transient.[22][23] Echinacea should not be taken by persons with progressive systemic and auto-immune disorders, connective tissue disorders, or related diseases. It should not be used with immunosuppressants or hepatotoxic drugs,[23][24] and has the potential to interfere with anesthesia.[25]

In one investigation by an independent consumer testing laboratory, five of eleven selected retail echinacea products failed quality testing. Four of the failing products contained measured levels of phenols believed to be related to potency below the levels stated on the labels. One failing product was contaminated with lead.[19]

Other uses

Some species of echinacea, notably E. purpurea, E. angustifolia, and E. pallida, are grown as ornamental plants in gardens.[26] They tolerate a wide variety of conditions, maintain attractive foliage throughout the season, and multiply rapidly. Appropriate species are used in prairie restorations.

References

  1. ^ Sunset Western Garden Book, 1995:606–607
  2. ^ http://www.efloras.org/florataxon.aspx?flora_id=1&taxon_id=111203
  3. ^ Plowden, Celeste. A manual of plant names. London, Allen and Unwin, 1972.. pp. 47. ISBN 0-04-580008-1. 
  4. ^ Screening of nine Echinacea supplements for antitumor activity using the potato disc bioassay, CHARDONNET C. O.; CHARRON C. S.; SAMS C. E.; CONWAY W. S. [1]
  5. ^ Barnes J, Anderson LA, Gibbons S, Phillipson JD. Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt.,Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties. J Pharm Pharmacol. 2005 Aug;57(8):929-54.
  6. ^ Laasonen M, Wennberg T, Harmia-Pulkkinen T, Vuorela H. Simultaneous analysis of alkamides and caffeic acid derivatives for the identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium roots. Planta Med. 2002 Jun;68(6):572-4.
  7. ^ a b Study: Echinacea Cuts Colds by Half WebMD Health News, June 26, 2007
  8. ^ a b Turner, Ronald B.; Rudolf Bauer, Karin Woelkart, Thomas C. Hulsey, and J. David Gangemi (2005-07-28). "An Evaluation of Echinacea angustifolia in Experimental Rhinovirus Infections". The New England Journal of Medicine 353 (4): 341–348. doi:10.1056/NEJMoa044441. ISSN 0028-4793. PMID 16049208. 
  9. ^ New Study on Echinacea is Faulty, says Canadian-Based Company Medical News Today, August 15, 2005
  10. ^ Paul Bergner. "Healing Power of Echinacea and Goldenseal and Other Immune System Herbs" (The Healing Power)1997
  11. ^ Human Medicines - Herbal Medicinal Products
  12. ^ EMEA Monograph on Echinacea purpurea
  13. ^ Shah SA, Sander S, White CM, Rinaldi M, Coleman CI. Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis.Lancet Infect Dis. 2007 Jul;7(7):473-80. [2]
  14. ^ Caruso TJ, Gwaltney JM (Mar 2005). "Treatment of the common cold with echinacea: a structured review". Clin. Infect. Dis. 40 (6): 807–10. doi:10.1086/428061. ISSN 1058-4838. PMID 15736012. 
  15. ^ Wishart, David J. (2007). Encyclopedia of the Great Plains Indians. U of Nebraska Press. pp. 156. ISBN 9780803298620. 
  16. ^ Moerman, Daniel E. (1998). Native American Ethnobotany. Timber Press. pp. 205. ISBN 9780881924534. http://books.google.com/books?id=UXaQat5icHUC&pg=PA205. 
  17. ^ Edible and Medicinal Plants of the West, Gregory L. Tilford, ISBN 0-87842-359-1
  18. ^ Linde K, Barrett B, Wölkart K, Bauer R, Melchart D (Jan 2006). "Echinacea for preventing and treating the common cold". Cochrane Database Syst Rev (1): CD000530. doi:10.1002/14651858.CD000530.pub2. PMID 16437427. 
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