Results for Enzyme-linked Immunosorbent Assay (ELISA)
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n

The abbreviation for immuno-globulin A.

 
 
Medical Test: Enzyme-linked Immunosorbent Assay (ELISA)

General information

Where It's Done Who Does It How Long It Takes Discomfort/Pain
Hospital or commercial laboratory. Doctor, nurse, or lab technician. Less than 5 minutes. Minor discomfort associated with drawing blood.

Results Ready When Special Equipment Risks/Complications Average Cost
7-14 days. Supplies for drawing blood. Negligible. $ per antibody.

Other names

IgA, IgG, or IgM antibody testing.

Purpose
  • To monitor treatment for an insect allergy.
  • To measure antibodies that develop in certain infectious diseases, such as aspergillosis, a fungal lung infection, or AIDS.
  • To measure the levels of antibodies other than IgE in the blood.
  • Rarely used for diagnosis of an allergy.
How it works

A sample of blood serum is applied to a plastic disk to which the test antigen or allergen is attached. An enzyme-linked marker is added, which causes a color change if your serum contains antibodies to the antigen tested.

Preparation

None.

Test procedure

Blood is drawn from your vein and sent to a laboratory for analysis.

After the test

Follow procedures for venous blood drawing.

Factors affecting results

High levels of one type of antibody may prevent low levels of another antibody against the same substance from being detected.

Interpretation

The test demonstrates the amount of IgA, IgG, and IgM antibodies in a milliliter of serum. Interpretation varies with the reason for the test. Since treatment of insect allergies leads to production of IgG, a high level can mean that the treatment is successful. Similarly, since IgG is produced in response to an aspergillosis infection, a high level indicates a recent infection.

Advantages
  • It's relatively inexpensive.
  • No radioactive materials are involved.
Disadvantages

It does not detect IgE, the antibody most commonly involved in allergic reactions.

The next step
  • No further testing is necessary, except for monitoring purposes.
  • If immunodeficiency is suspected and levels of IgAs are normal, you will be vaccinated and the response to the vaccine will be monitored.
 
 

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Copyrights:

Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved.  Read more
Medical Test. The Patient's Guide to Medical Tests by Faculty Members at The Yale University of Medicine and G.S. Sharpe Communications, Inc. Copyright © 1997 by Yale University of Medicine and G.S. Sharpe Communications, Inc. Published by Houghton Mifflin Company. All rights reserved.  Read more

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