eosinophilic granuloma

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(medicine) A disease, principally of childhood, characterized by foci of bone inflammation and granulation containing lipids, mononuclear cells, and eosinophils.

A granulomatous inflammatory disease of unknown etiology, usually monofocal in bone but sometimes affecting soft tissues. Sheets of histiocytes and masses of eosinophils characterize the lesion histologically

A lesion having numerous histiocytes that may contain Langerhans granules, eosinophils, and pockets of necrosis. It is usually a solitary bone lesion but may develop in the lung.