Ernst Stavro Blofeld was created in 1961.

Christopher Plummer

No, Ernst Stavro Blofeld (Charles Gray) returns to die another day in For Your Eyes Only (1981), where James Bond (Roger Moore) drops him down a chimney with a helicopter.

I think that all of James Bond's old recurring adversary have either vanished, become allies or died. The James Bond villain that appears in the most James Bond films is probably Ernst Stavro Blofeld.

A bald-headed assassin confined to a wheelchair whose identity is kept secret but who is presumably Ernst Stavro Blofeld.