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two loci on human chromosomes 1 and 14 respectively that are linked to migraine headaches. The locus on chromosome 1q23 has been linked to familial hemiplegic migraine type 2, while the locus on chromosome 14q21 is associated with migraine without aura

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two loci on human chromosomes 1 and 14 respectively that are linked to migraine headaches. The locus on chromosome 1q23 has been linked to familial hemiplegic migraine type 2, while the locus on chromosome 14q21 is associated with migraine without aura

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Hemiplegic migraines affect a very small percentage of people in the United States. People with hemiplegic migraines experience paralysis or weakness on one side of the body, disturbances in speech and vision, and other symptoms that often mimic a stroke.

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A migraine that causes paralysis in one side of the body is called a hemiplegic migraine. There are two kinds: Familial, where you'll have a family history, and sporadic - which can happen to anyone. It becomes very important to get the proper diagnosis of hemiplegic migraine, because if you have this particular kind of migraine you cannot use vasoconstricting medications such as the triptans (Imitrex, Zomig, etc..) or DHE (Dihydroergotamine, also found in Migranal nasal spray.) Normal migraines with aura can also cause numbness and confusion, but they will not cause the paralysis. One of the main forms of prevention for hemiplegic migraines are the calcium-channel blockers, as there may be a faulty gene responsible for the disruption of calcium in the cell, causing neurons to misfire. Verapamil is the only calcium-channel blocker approved for migraine prophylaxis at this time. Generally these medications will be paired with anti-epileptic medications such as Topamax or Zonegran. If you do have hemiplegic migraines, you should be under the care of a headache specialist.

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Hemiplegic migraines are a specialized migraine variant. They come with specific symptoms not seen in common or classic migraines.

There are two types of hemiplegic migraines, familial and sporadic.

Besides the normal migraine symptoms (photophobia, nausea, visual aura, etc..), people with hemiplegic migraines experience some or all of the following:

During the aura phase they may experience:

* The paralysis of the limbs on one side of their body (hemiplegia) * Numbness, tingling. * Motor weakness * Speech impairment (slurring or inability to find a word) * Impaired Consciousness (ranges from confusion to coma) * Fever * Symptoms of Meningitis

The symptoms of hemiplegic migraine can come on very suddenly. Because of this and the severity of these symptoms, and how they mimic many other dangerous problems such as stroke, it is recommended that hemiplegic migraineurs wear a medic alert bracelet.

The paralysis can last the entire length of the headache phase, the headache may start before paralysis begins, or head pain may be absent altogether.

The hemiplegic visual aura can be prolonged, and sometimes may even last weeks.

Currently, many of the abortive medications used in treating classic and common migraines are contraindicated in treating hemiplegic migraine. This is because of the stroke concern, as migraineurs who have such severe headaches with prolonged aura - have a higher stroke risk. For preventative medication, calcium-channel blockers tend to see the most success. So many hemiplegic migraineurs are being prescribed Verapamil, sometimes pairing that with Topamax to lower the frequency of the migraines even further.

It is essential to be working with a headache specialist when you have been diagnosed with hemiplegic migraines.

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Familial means hereditary, running in families, hence predictable at times. Sporadic means randomly caused, with no heredity that an be traced, usually by a mutation in the same gene that causes the familial form of the disorder.

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