An insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.
- f.–fibrinogen degradation products (FDPs) — the breakdown products of fibrin and fibrinogen, resulting from activation of the fibrinolytic system, they inhibit fibrin formation and platelet adherence. Elevated levels are found in the blood and urine in association with disseminated intravascular coagulation and detection is a test for that condition.
- f.–fibrinogen split products — see fibrin–fibrinogen degradation products (above).
- f. foam — a clot promoting surgical material for application to oozing surfaces. Strips of fine white sponge to be soaked in thrombin solution before application.
- f. glue — a mixture of bovine thrombin and concentrated fibrinogen. It may be used topically or by injection in management of hemostasis.
- f. plate method — a method of measuring fibrinolytic activity by incubating a fibrin clot with test serum in a Petri dish.
- soluble f. monomers — a stage in the clot formation process of producing insoluble fibrin monomers.
- f. stabilizing factor — see fibrin stabilizing factor.
