
Excessive formation of fibrous connective tissue. In sport, overtraining can lead to muscle fibrosis, with adhesions developing between muscle fibres and cross linkages forming between muscle fascia in the overused muscles. Fibrosis may cause local pain and reduce the ability of the affected muscle to contract and relax rapidly.
Formation of fibrous tissue; fibroid degeneration.
1. the process of forming fibrous tissue, usually by degeneration (for example, fibrosis of the pulp). The process occurs normally in the formation of scar tissue to replace normal tissue lost through injury or infection. 2. an abnormal condition in which fibrous connective tissue spreads over or replaces normal smooth muscle or other normal organ tissue. Fibrosis is most common in the heart, lung, peritoneum, and kidney.

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| Fibrosis | |
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| Classification and external resources | |
Micrograph of a heart showing fibrosis (yellow - left of image) and amyloid deposition (brown - right of image). Movat's stain. |
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| MeSH | D005355 |
Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This is as opposed to formation of fibrous tissue as a normal constituent of an organ or tissue. Scarring is confluent fibrosis that obliterates the architecture of the underlying organ or tissue.
The term is also sometimes used to describe a normal healing process,[1] but this usage is less common.
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Contents
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| Type | Most common location(s) | Circumscription | Cellularity | Vascularity and nature of vessels | Appearance of collagen | Elastic fibers | Picture |
|---|---|---|---|---|---|---|---|
| Nuchal fibroma | Nuchal region | No | Very low | Very low | Bundles of fibers | Scant | |
| Collagenous fibroma | Shoulder girdle, extremities | Yes, by macroscopic appearance, but microscopically infiltrative | Increased but generally low | Low | Scant or absent | Amorphous | |
| Fibroma of tendon sheath | Distal extremities, especially the hand | Yes | Low to high | Moderate to high, with some slitlike vessels | Amorphous | Absent | |
| Scar | Variable | Variable | Low to high | Variable | Amorphous | Scant to absent | |
| Elastofibroma | Subscapular chest wall | No | Low to moderate | Low | Amorphous | Abundant and abnormal | |
| Desmoid-type fibromatosis | Abdominal wall, shoulder girdle | Yes, by macroscopic appearance, but microscopically infiltrative | Moderate | Moderate, mildly dilated | Amorphous | Absent | |
| Keloid | Upper part of back, deltoid, presternal, ear lobes | No | Some fibroblasts | Low | Amorphous thick eosinophilic bundles | Scant or Absent |
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Nederlands (Dutch)
fibrose (ziekte van vezelachtig weefsel)
Français (French)
n. - cellulite
Deutsch (German)
n. - (Med.) Fibrosis (Gewebeverstopfung)
Ελληνική (Greek)
n. - (παθολ.) ίνωση
Português (Portuguese)
n. - fibrose (f) (Med.)
Español (Spanish)
n. - fibrosis
Svenska (Swedish)
n. - fibros (med.)
中文(简体)(Chinese (Simplified))
纤维症, 纤维化
中文(繁體)(Chinese (Traditional))
n. - 纖維症, 纖維化
日本語 (Japanese)
n. - 繊維症, 繊維形成, 線維症
العربيه (Arabic)
(الاسم) التليف
עברית (Hebrew)
n. - לייפת (ברפואה), התעבות של ריקמה מחברת
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