fibrosis

fi·bro·sis

(fī-brō'sĭs) pronunciation

n.
The formation of excessive fibrous tissue, as in a reparative or reactive process.

fibrotic fi·brot'ic (-brŏt'ĭk) adj.

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fibrosis

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focal tissue thickening

Excessive formation of fibrous connective tissue. In sport, overtraining can lead to muscle fibrosis, with adhesions developing between muscle fibres and cross linkages forming between muscle fascia in the overused muscles. Fibrosis may cause local pain and reduce the ability of the affected muscle to contract and relax rapidly.

Saunders Veterinary Dictionary:

fibrosis

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Formation of fibrous tissue; fibroid degeneration.

postfibrinous f. — that occurring in tissues in which fibrin has been previously deposited.
proliferative f. — that in which the fibrous elements continue to proliferate after the original causative factor has ceased to operate.

Mosby's Dental Dictionary:

fibrosis

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(fībrō′sis)
n

1. the process of forming fibrous tissue, usually by degeneration (for example, fibrosis of the pulp). The process occurs normally in the formation of scar tissue to replace normal tissue lost through injury or infection. 2. an abnormal condition in which fibrous connective tissue spreads over or replaces normal smooth muscle or other normal organ tissue. Fibrosis is most common in the heart, lung, peritoneum, and kidney.

Random House Word Menu:

categories related to 'fibrosis'

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For a list of words related to fibrosis, see:

Afflictions and Conditions - fibrosis: thickening and scarring of connective tissue due to injury or inflammation

Wikipedia on Answers.com:

Fibrosis

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Fibrosis
Classification and external resources
Micrograph of a heart showing fibrosis (yellow - left of image) and amyloid deposition (brown - right of image). Movat's stain.
MeSH	D005355

Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This is as opposed to formation of fibrous tissue as a normal constituent of an organ or tissue. Scarring is confluent fibrosis that obliterates the architecture of the underlying organ or tissue.

The term is also sometimes used to describe a normal healing process,^[1] but this usage is less common.

Contents

1 Examples of fibrosis
2 Types
3 References
4 External links

Examples of fibrosis

Micrograph showing cirrhosis of the liver. The tissue in this example is stained with a trichrome stain, in which fibrosis is colored blue. The red areas are the nodular liver tissue

Pulmonary fibrosis (lungs)
- Idiopathic pulmonary fibrosis (where the cause is unknown)
- Cystic fibrosis
Cirrhosis (liver)
Endomyocardial fibrosis (heart)
Mediastinal fibrosis (soft tissue of the mediastinum)
Myelofibrosis (bone marrow)
Retroperitoneal fibrosis (soft tissue of the retroperitoneum)
Progressive massive fibrosis (lungs); a complication of coal workers' pneumoconiosis
Nephrogenic systemic fibrosis (skin)
Crohn's Disease (intestine)
Keloid (skin)
Old myocardial infarction (heart)
Scleroderma/systemic sclerosis (skin, lungs)
Arthrofibrosis (knee, shoulder, other joints)
Some forms of adhesive capsulitis (shoulder)

Types

Type	Most common location(s)	Circumscription	Cellularity	Vascularity and nature of vessels	Appearance of collagen	Elastic fibers
Nuchal fibroma	Nuchal region	No	Very low	Very low	Bundles of fibers	Scant
Collagenous fibroma	Shoulder girdle, extremities	Yes, by macroscopic appearance, but microscopically infiltrative	Increased but generally low	Low	Scant or absent	Amorphous
Fibroma of tendon sheath	Distal extremities, especially the hand	Yes	Low to high	Moderate to high, with some slitlike vessels	Amorphous	Absent
Scar	Variable	Variable	Low to high	Variable	Amorphous	Scant to absent
Elastofibroma	Subscapular chest wall	No	Low to moderate	Low	Amorphous	Abundant and abnormal
Desmoid-type fibromatosis	Abdominal wall, shoulder girdle	Yes, by macroscopic appearance, but microscopically infiltrative	Moderate	Moderate, mildly dilated	Amorphous	Absent
Keloid	Upper part of back, deltoid, presternal, ear lobes	No	Some fibroblasts	Low	Amorphous thick eosinophilic bundles	Scant or Absent

^[2]^[3]

References

^ Glossary of dermatopathological terms. DermNet NZ
^ Nuchal-type fibroma. Cancer. Volume 85, Issue 1, pp. 156-163.
^ Skin Pathology. David Weedon. Second Edition.

External links

"Fibrosis" at Dorland's Medical Dictionary

International Scar Meeting in Tokyo 2010 International Scar Meeting

v d e Wound healing

Blood vessels	Angiogenesis · Vasculogenesis · Intussusception

Other	Fibrosis · Maggot therapy · Granulation tissue · Growth factor · Scar · Stem cell

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Translations:

Fibrosis

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Dansk (Danish)
n. - fibrosis

Nederlands (Dutch)
fibrose (ziekte van vezelachtig weefsel)

Français (French)
n. - cellulite

Deutsch (German)
n. - (Med.) Fibrosis (Gewebeverstopfung)

Ελληνική (Greek)
n. - (παθολ.) ίνωση

Italiano (Italian)
fibrosi

Português (Portuguese)
n. - fibrose (f) (Med.)

Русский (Russian)
фиброз

Español (Spanish)
n. - fibrosis

Svenska (Swedish)
n. - fibros (med.)

中文（简体）(Chinese (Simplified))
纤维症, 纤维化

中文（繁體）(Chinese (Traditional))
n. - 纖維症, 纖維化

한국어 (Korean)
n. - 섬유증

日本語 (Japanese)
n. - 繊維症, 繊維形成, 線維症

العربيه (Arabic)
‏(الاسم) التليف‏

עברית (Hebrew)
n. - ‮לייפת (ברפואה), התעבות של ריקמה מחברת‬

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		American Heritage Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved. Read more
		Oxford Dictionary of Sports Science & Medicine. The Oxford Dictionary of Sports Science & Medicine. Copyright © Michael Kent 1998, 2006, 2007. All rights reserved. Read more
		Saunders Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more
		Mosby's Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved. Read more
		Random House Word Menu. © 2010 Write Brothers Inc. Word Menu is a registered trademark of the Estate of Stephen Glazier. Write Brothers Inc. All rights reserved. Read more
		Wikipedia on Answers.com. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article Fibrosis. Read more
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