Francis Locke (October 31, 1766 – January 8, 1823) was a U.S. senator from the state of North Carolina. Francis Locke was the son of Francis Locke (1722-1796, who was in the Revolutionary War) and Anne Brandon (b.abt. 1737). They are all buried at Thyatira Cemetery in Rowan County, North Carolina.
A native of Rowan County, North Carolina and a judge of the Superior Court of North Carolina from 1803 to 1814, he was elected to the Senate in 1814 to fill a vacancy caused by the resignation of David Stone, but resigned in 1815, before he could qualify.
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| United States Senate | ||
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| Preceded by David Stone |
United States Senator (Class 3) from North Carolina 1814–1815 Served alongside: James Turner |
Succeeded by Nathaniel Macon |
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