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germ

  (jûrm) pronunciation
n.
  1. Biology. A small mass of protoplasm or cells from which a new organism or one of its parts may develop.
  2. The earliest form of an organism; a seed, bud, or spore.
  3. A microorganism, especially a pathogen.
  4. Something that may serve as the basis of further growth or development: the germ of a project.

[Middle English, bud, from Old French germe, from Latin germen.]


 
 

In the food world, the word "germ" refers to a grain (like wheat) kernel's nucleus or embryo. Wheat germ is one of the more commercially popular types on the market. The nutritiously endowed germ furnishes thiamine, vitamin E, iron and riboflavin.

 
Thesaurus: germ

noun

  1. A minute organism usually producing disease: bug, microbe, microorganism. See beings.
  2. A source of further growth and development: bud1, embryo, kernel, nucleus, seed, spark1. See start/end.

 

Microorganisms that can cause disease or infection.

 

1. old-fashioned and lay term for a pathogenic microorganism.
2. living substance capable of developing into an organ, part or organism as a whole; a primordium. Commonly used to refer to the embryos of wheat grains which are removed during milling and sold separately as wheat germ.

  • g. cell — direct descendants of the primordial cells which originate from the yolk sac endoderm and migrate to the gonadal ridges of the embryo, where they give rise to either ova or spermatozoa. Called also gonocytes, sex cells.
  • g. cell tumor — a rare tumor in dogs, similar to more common lesions in humans. Similar to pituitary adenomas in distribution and cellular characteristics.
  • g. line — the genetic material as it is transferred via the gametes, before being modified by somatic recombination or mutation.
  • g. line cells — gametes.
  • g. line transmission — a mode of transmission, particularly of retroviruses, whereby the genome of the virus is integrated into the chromosomal DNA and transmitted via gametes to offspring.
  • g. plasma evaluation program — a planned investigative, large scale breeding program aimed at accumulating comparative information on the relative performance of various breeds and crossbreeds of agricultural animals.
  • g. theory — 1. all organisms are developed from a cell.
  • — 2. infectious diseases are of microbial origin.
  • g. tube — a tube-like structure that develops during the growth of some fungi and becomes a hypha; a feature of the yeast, Candida albicans.
  • wheat g. — see wheat germ.


 
Essay: The germ theory of disease

In the middle of the 19th century, some surgeons realized that doctors could spread disease from one person to another. Ignaz Semmelweiss in 1847 reduced the number of cases of childbed fever by having surgeons wash their hands between deliveries. Joseph Lister in 1865 went further and proposed using carbolic acid (also called phenol) on patients' wounds during surgery.

Doctors were not the only agents spreading disease, of course. John Snow, a doctor in London, noticed that cholera cases were clustered where people used water from particular sources. He persuaded the authorities to remove the pump handle from a well at the center of the largest outbreak area; the number of cases in that area dropped immediately. William Budd learned of Snow's success and repeated it, stopping a cholera epidemic in Bristol in 1866 by managing the town's water supply.

Louis Pasteur urged French army surgeons to sterilize their instruments and their patients during the Franco-Prussian War of 1870. After the war, Pasteur began an extensive study of the causes of disease. He started with anthrax--a disease that affects both farm animals and humans--because another proponent of the newly developing germ theory of disease, Robert Koch, had already found the bacterium that causes anthrax in 1876. Pasteur first helped stop the spread of anthrax by proposing sterilization and burial of the bodies of animals that had died from it. Later he was to find something even more effective.

In 1879 Pasteur discovered by accident that bacteria could be weakened. In their weakened state, they failed to cause disease but still provoked immunity. He soon learned that the anthrax bacterium could be weakened in this way and by 1881 was able to demonstrate that an effective immunization against anthrax resulted from injection with the weakened bacteria. Pasteur called the process of producing immunization in this way vaccination, in recognition of Edward Jenner's use of cowpox (vaccinia) to prevent smallpox. Pasteur, Koch, and others developed vaccines of varying degrees of effectiveness against many of the major communicable diseases of the time--cholera, tuberculosis, tetanus, diphtheria, rabies.

Originally the germ theory applied only to bacteria, but about the same time as Pasteur was writing his major exposition of the theory, Charles Laveran discovered that the organism causing malaria is a protist (sometimes called a protozoan), not a bacterium. The agents of some diseases, especially skin diseases, may be fungi. In other communicable diseases, such as measles, neither a bacterium, protist, nor fungus could be found in the late 19th or early 20th centuries. Because of the success of the germ theory, organisms too small to be seen or trapped in filters--filterable viruses--were postulated to explain these diseases. With the invention of the electron microscope in the 20th century, such viruses were finally observed directly.

Today the germ theory of disease is so entrenched that even diseases that are not communicable--such as cancer, diabetes, and multiple sclerosis--are suspected of being caused by some "germ."

 
Wikipedia: germ (mathematics)

In mathematics, a germ of (continuous, differentiable or analytic) functions is an equivalence class of (continuous, differentiable or analytic) functions from a topological space to another (often from the real line to itself), grouped together on the basis of their equality on the neighborhood of a fixed reference point in their domain of definition. In the same way, a germ of sets is an equivalence class of subsets of a given topological space, grouped together on the basis of their equality on the neighborhood of a fixed reference point belonging to all of them.

The name is a pun (or continuation of the sheaf metaphor) on cereal germ, as a germ is the "heart" of a function, as it is for a grain.

Formal definition

Basic definition

Two functions f and g between the same topological space X and a set Y are said to be equivalent near a point x in their domain, if there is some open neighborhood U of x in X on which they agree, i.e.

f(x') = g(x') \quad \forall x'\in U\iff f|_U=g|_U \iff f \sim_x g

This is an equivalence relation on the space YX = Hom(X,Y) of maps between X and Y. For the proof, it is sufficient to note that equality is used in its definition: then reflexivity and symmetry are immediate consequences. For transitivity, given functions f,g,h such that f = g on U and g = h on V, then f = g = h on UV.

The equivalence classes have the following form

[f]_x=\left\{g \in Y^X\mid f \sim_x g\right\}\,

Then the space of germs of functions at xX, is the quotient set

\Gamma_{x_0}=Y^X/\!\!\sim_x\;=\left\{[f]_x \mid f\in Y^X\right\}\,

As it can be easily seen, the germ at x is the stalk of the sheaf of functions at x.

The basic definition of germ does not require a topology on the codomain: a topology is only necessary to define neighborhoods of points in the domain. Similarly, it does not require any continuity or smoothness condition on the functions. With even more generality, functions can only be defined on a neighborhood U of the given point Failed to parse (unknown function\scriptstyle): \scriptstyle x \in X

and need not be restrictions of globally defined functions, so only a presheaf is needed to define germs. Since the stalks of a presheaf agree with the stalks of its sheafification (indeed, a construction of sheafification uses the sheaf of stalks of the given presheaf), the wording stalks of a sheaf is commonly used.

Germs of various classes of functions

If X and Y have additional structure, it is possible to define subsets of YX, or more generally sub-presheaves of a given presheaf Failed to parse (unknown function\scriptstyle): \scriptstyle\mathcal{F}

and corresponding germs: some notable examples follow.
C^0(X,Y) \subset \mbox{Hom}(X,Y)\,
of continuous functions defines germs of continuous functions.
C^k(X,Y) \subset \mbox{Hom}(X,Y)\,
of k-times continuously differentiable functions, the subset
C^\infty(X,Y)=\bigcap_k C^k(X,Y)\subset \mbox{Hom}(X,Y)\,
of smooth functions and the subset
C^\omega(X,Y)\subset \mbox{Hom}(X,Y)
of analytic functions can be defined (ω here is the ordinal for infinity; this is an abuse of notation, by analogy with Ck and C), and then spaces of germs of (finitely) differentiable, smooth, analytic functions can be constructed.
  • If X,Y have an algebraic structure, then regular (and rational) functions between them can be defined, and germs of regular functions (and likewise rational) can be defined.

Germs of various classes of sets

Two subsets V,W of a topological space X are said to be equivalent near a point x belonging to them if there is some open neighborhood U of x in X such that

U \cap V = U \cap W \iff V \cong_x\! W

This is equivalent to say that the germs of the characteristic functions of the two subsets are equal, i.e.

V \cong_x\! W \iff \chi_V \sim_x \chi_W

In more abstract terms, the contravariant functor which maps a set to its power set is representable by the set Y = {0,1}, i.e. is naturally isomorphic to the hom functor Hom( - ,Y). Consequently, for a given set X, it is possible to alternatively analyze or its subsets or functions belonging to Hom(X,Y) where Y = {0,1}, since those objects are isomorphic.

Notably, if x is in the interior of both V and W, then they are equivalent near x.

This is an equivalence relation on the power set of the topological space X, to which V and W both belong: the equivalence classes have the following form

V_x=\left\{W \in \mathcal{P}(X)|\, V \cong_x\! W\right\}\,

Then the space of germs of sets at x in X is the quotient set

X_x=X/\!\!\cong_x\;=\left\{V_x|V\in \mathcal{P}(X)\right\}\,\,

Various spaces of germs of sets can be defined in the same way as it can be done for germs of functions. Anyway, the space of germs of a variety is the most frequently encountered in standard mathematical research: the subset of the power set of the topological space X used in its construction is the class of analytic varieties.

Notation

The stalk of a sheaf Failed to parse (unknown function\scriptstyle): \scriptstyle\mathcal{F}

on a topological space X at a point x of X is commonly denoted by Failed to parse (unknown function\scriptstyle):  \scriptstyle\mathcal{F}_x 

. As a consequence germs, being stalks of sheaves of various kind of functions, borrow this scheme of notation:

  • \mathcal{C}_x^0\, is the space of germs of continuous functions at x.
  • \mathcal{C}_x^k\, for each natural number k is the space of germs of k-times-differentiable functions at x.
  • \mathcal{C}_x^\infty\, is the space of germs of infinitely differentiable ("smooth") functions at x.
  • \mathcal{C}_x^\omega\, is the space of germs of analytic functions at x.
  • \mathcal{O}_x\, is the space of germs of holomorphic functions (in complex geometry), or space of germs of regular functions (in algebraic geometry) at x.

For germs of sets and varieties, the notation is not so well established: some notations found in literature include:

  • \mathfrak{V}_x\, is the space of germs of analytic varieties at x.

When the point x is fixed and known (e.g. when X is a topological vector space and x = 0), it can be dropped in each of the above symbols: also, when dimX = n, a subscript before the symbol can be added. As example

  • Failed to parse (syntax error): {_n\mathcal{C}^0},{_n\mathcal{C}^k},{_n\mathcal{C}^\infty},{_n\mathcal{C}^\omega},{_n\mathcal{O}},{_n\mathfrak{V}}\,
are the spaces of germs shown above when X is a n-dimensional vector space and x = 0.

Applications

The key word in the applications of germs is locality: all local properties of a function at a point can be studied analyzing its germ. They are a generalization of Taylor series, and indeed the Taylor series of a germ (of a differentiable function) is defined: you only need local information to compute derivatives.

Germs are useful in determining the properties of dynamical systems near chosen points of their phase space: they are one of the main tools in singularity theory and catastrophe theory.

When the topological spaces considered are Riemann surfaces or more generally analytic varieties, germs of holomorphic functions on them can be viewed as power series, and thus the set of germs can be considered to be the analytic continuation of an analytic function.

See also

References

  • Nicolas Bourbaki (1989). General Topology. Chapters 1-4, paperback ed., Springer-Verlag. ISBN 3-540-64241-2. , chapter I, paragraph 6, subparagraph 10 "Germs at a point".
  • Raghavan Narsimhan (1973). Analysis on Real and Complex Manifolds, 2nd ed., North-Holland Elsevier. ISBN 0-7204-2501-8. , chapter 2, paragraph 2.1, "Basic Definitions".
  • Robert C. Gunning and Hugo Rossi (1965). Analytic Functions of Several Complex Variables. Prentice-Hall. , chapter 2 "Local Rings of Holomorphic Functions", especially paragraph A "The Elementary Properties of the Local Rings" and paragraph E "Germs of Varieties".
  • Giuseppe Tallini (1973). Varietà differenziabili e coomologia di De Rham (Differentiable manifolds and De Rham cohomology). Edizioni Cremonese. ISBN 88-7083413-1. , paragraph 31, "Germi di funzioni differenziabili in un punto P di Vn (Germs of differentiable functions at a point P of Vn)" (in Italian).

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Dansk (Danish)
n. - bakterie, smittekim, mikrobe, spire

idioms:

  • germ warfare    biologisk krigsførelse
  • the germ of    kimen til

Nederlands (Dutch)
bacil, (ziekte)kiem, grondgedachte

Français (French)
n. - microbe, (lit, fig) germe

idioms:

  • germ warfare    guerre bactériologique
  • the germ of    le germe de

Deutsch (German)
n. - Keim, Krankheitserreger

idioms:

  • germ warfare    biologische Kriegsführung
  • the germ of    der Ansatz für

Ελληνική (Greek)
n. - (βιολ.) σπέρμα, μικρόβιο, (μτφ.) αρχική αιτία, σπέρμα

idioms:

  • germ warfare    (στρατ.) μικροβιολογικός πόλεμος
  • the germ of    το σπέρμα (π.χ. μιας ιδέας)

Italiano (Italian)
germe, bacillo

idioms:

  • germ warfare    guerra batteriologica
  • the germ of    l'inizio di

Português (Portuguese)
n. - micróbio (m), embrião (m), semente (f), origem (f)

idioms:

  • germ warfare    guerra (f) bacteriológica (Mil.)
  • the germ of    a origem (f) de

Русский (Russian)
микроб, эмбрион, завязь, давать ростки

idioms:

  • germ warfare    бактериологическая война
  • the germ of    зародыш, зарождение чего-л.

Español (Spanish)
n. - germen, bacilo, microbio, bacteria

idioms:

  • germ warfare    guerra bacteriológica
  • the germ of    algo que está por desarrollarse

Svenska (Swedish)
n. - embryo, bakterie, frö

中文(简体) (Chinese (Simplified))
细菌, 根源, 种子

idioms:

  • germ warfare    细菌战争
  • the germ of    一种...的起源

中文(繁體) (Chinese (Traditional))
n. - 細菌, 根源, 種子

idioms:

  • germ warfare    細菌戰爭
  • the germ of    一種...的起源

한국어 (Korean)
n. - 세균, 배[종], 기원

idioms:

  • the germ of    ~의 기원으로

日本語 (Japanese)
n. - 胚, 微生物, 細菌, 病原菌, 芽生え, 根源, 芽
v. - 芽を出す, 開く

idioms:

  • germ warfare    細菌戦
  • the germ of    初期に

العربيه (Arabic)
‏(الاسم) جرثومه‏

עברית (Hebrew)
n. - ‮חיידק, נבט, התהוות, ראשית‬


 
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Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2007. Published by Houghton Mifflin Company. All rights reserved.  Read more
Food Lover's Companion. Food Lover's Companion. Copyright © 2001 by Barron's Educational Series, Inc. All rights reserved.  Read more
Thesaurus. Roget's II: The New Thesaurus, Third Edition by the Editors of the American Heritage® Dictionary Copyright © 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.  Read more
Health Dictionary. The New Dictionary of Cultural Literacy, Third Edition Edited by E.D. Hirsch, Jr., Joseph F. Kett, and James Trefil. Copyright © 2002 by Houghton Mifflin Company. Published by Houghton Mifflin. All rights reserved.  Read more
Veterinary Dictionary. The Veterinary Dictionary. Copyright © 2007 by Elsevier. All rights reserved.  Read more
Essay. History of Science and Technology, edited by Bryan Bunch and Alexander Hellemans. Copyright © 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Germ (mathematics)" Read more
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