1. Pains in the limbs and joints of children or adolescents, often attributed to rapid growth but arising from various unrelated causes.
2. Emotional difficulties that occur during adolescence.
3. Problems that arise in the initiation or enlargement of an enterprise.

The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.