The Helios mission holds the record for fastest manmade object, it consisted of two spacecraft launched in the mid-1970s to study the Sun. The Helios 2 solar orbit result in a perihelion velocity of 153,800 mph the aphelion speed of Helios 2 is only 45,360 mph.
http://www.aerospaceweb.org/question/spacecraft/q0109c.shtml
The record for fastest interstellar spacecraft currently belongs to Voyager 1 it is exiting our solar system at a rate of about 38,600 mph.
http://www.aerospaceweb.org/question/spacecraft/q0260.shtml