A substance, such as an antibody, that causes agglutination of red blood cells.
[HEMAGGLUTIN(ATE) + -IN.]
Dictionary:
he·mag·glu·ti·nin (hē'mə-glūt'n-ĭn) ![]() |
[HEMAGGLUTIN(ATE) + -IN.]
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| Medical Dictionary: he·mag·glu·ti·nin |
| Veterinary Dictionary: hemagglutinin |
A substance that causes agglutination of erythrocytes. See hemagglutination.
| Wikipedia: Hemagglutinin |
Hemagglutinin refers to a substance that causes red blood cells to agglutinate. This process is called hemagglutination. Examples include antibodies[1], blood group antigens, autoimmune factors (such as Rh factor), and lectins[2]. Bacteria, viruses, and other parasites can be the source of blood agglutinins as well.
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Examples include:
Hemagglutination can be used to identify RBC surface antigens (with known antibodies) or to screen for antibodies (with RBCs with known surface antigens).
Using anti-A and anti-B antibodies that bind specifically to either the A or to the B blood group surface
The bedside card method of blood grouping relies on visual agglutination to determine an individual's blood group. The card has dried blood group antibody reagents fixed onto its surface and a drop of the individual's blood is placed on each area on the card. The presence or absence of visual agglutination enables a quick convenient method of determining the ABO and Rhesus status of the individual.
Agglutination of red blood cells is used in the Coombs test.
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