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they are related because of blood

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they are related because of blood

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a test for hemosiderin, utilizing Perls Prussian blue stain.

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ferritin, hemosiderin, and transferrin

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Hepatomegaly in thalassemia occures as aresult of engorgement of hepatic paranchymal and phagocytic cells with hemosiderin deposits.

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Hemosiderin is an iron-containing pigment derived in humans from ferritin. It can be found in macrophages in small amounts throughout a number of different tissues including the bone marrow, liver and the spleen as a normal way to store iron. Under certain conditions it can pathologically accumulate in excess amounts. In hemosiderosis macrophages are hemosiderin-laden but without associated damage to surrounding tissue. When there more extensive accumulation occurs, it can lead to surrounding tissue damage, scarring and organ dysfunction. This is called hemochromatosis.

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