I. Herbert Scheinberg has written:

'Wilson's disease' -- subject(s): Hepatolenticular degeneration

Charles Archibald Owen has written:

'Wilson's disease' -- subject(s): Hepatolenticular degeneration

it is a rare diorder of abnormal copper metabolism and is characterised by:

hepatolenticular degeneration.

copper get deposited in abnormal amounts in liver and lenticular nucleus of brain leading to necrosis of liver and brain.

low level of copper and ceruloplasmin in plasma with increased excretion of copper in urine,

copper deposition in kidneys causes renal damage.

causes:

failure in the synthesis of ceruloplasmin.

excess copper in plasma.

reduced intestinal excretion of copper.

treatment: penicillamine.

Senile myocardial degeneration is degeneration of the heart. Often a heart valve has to be replaced because of this degeneration.

My Degeneration was created in 2003.