I. Herbert Scheinberg has written:

'Wilson's disease' -- subject(s): Hepatolenticular degeneration

Charles Archibald Owen has written:

'Wilson's disease' -- subject(s): Hepatolenticular degeneration

it is a rare diorder of abnormal copper metabolism and is characterised by:

hepatolenticular degeneration.

copper get deposited in abnormal amounts in liver and lenticular nucleus of brain leading to necrosis of liver and brain.

low level of copper and ceruloplasmin in plasma with increased excretion of copper in urine,

copper deposition in kidneys causes renal damage.

causes:

failure in the synthesis of ceruloplasmin.

excess copper in plasma.

reduced intestinal excretion of copper.

treatment: penicillamine.

Wilson disease is also called hepatolenticular degeneration, referring to its effects on the liver ("hepato-") and lenticular nucleus (part of the basal ganglia of the brain). The disease is due to an inability to transport copper, and so deposits accumulate in several areas, including the lenticular nucleus, causing damage. The lenticular nucleus, which comprises the globus pallidus and putamen, is part of the brain's basal ganglia, and damage to it can give signs and symptoms of Parkinson disease. Other signs of parkinsonism may also be apparent in patients with Wilson disease; these include dementia and mood disorders.

Spinocerebellar Degeneration Disease has no known cause. Neither a source. :)