Histamine H-2 receptor blockers stop the action of histamine on the gastric parietal cells, inhibiting the secretion of gastric acid.

Histamine H-2 receptor blockers stop the action of histamine on the gastric parietal cells, inhibiting the secretion of gastric acid.

Zantac is H2 receptor antagonist, not a proton pump inhibitor. The H2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells.

http://www.medscape.com/viewarticle/503104_Figures This link listed above will bring you to a site that provides diagrams which illustrate the immune response. Zyrtec is an H1-receptor antagonist. Zyrtec appears to compete with the histamine molecule (produced by mast cells) for cellular binding sites... so the histamine lacking for an available binding site does not have a chance to trigger a series of events which result in the allergic symptoms we experience.

Histamine H-2 receptor blockers act by stopping the pathway that leads to the secretion of stomach acid.