HLA typing

Human leukocyte antigens, organ donor or transplant tissue typing, lymphocyte cross match, and histocompatibility testing.

• To identify surface groups of proteins known as human leukocyte antigens (HLAs), which are unique in each person.
• To match HLA types of organ donor and recipient, which lowers the risk of organ rejection.
• To help determine paternity, since HLA systems are inherited.
• To help diagnose ankylosing spondylitis and sacroiliitis, which are often associated with an HLA called HLA-B27.

HLAs detectable in blood provide clues to immune conditions.

None.

A blood sample is drawn and sent to a laboratory for analysis.

Follow procedure for drawing blood.

None.

• If done for organ transplantation, HLA type will be compared to those of available organs.
• Blood may be analyzed for particular HLAs that indicate disease.
• To determine paternity, a child's HLA type is compared to that of a possible father.

• There's no risk.
• It improves results of organ transplantation.

None.

• After a positive test, if done to confirm ankylosing spondylitis or sacroiliitis, X-rays of the spine or sacroiliac joints may be done and treatment begun.
• If done for donor matching, transplant can proceed if match is good.