Results for imiglucerase
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Drug Info:

Imiglucerase

Brand names: Cerezyme®



Imiglucerase injection

What is imiglucerase injection?

IMIGLUCERASE (Cerezyme®) replaces a naturally occuring enzyme that is missing in patients with Gaucher's disease. This enzyme helps with fat breakdown in the body. It helps keep blood contents at normal levels, and it may help prevent your liver or spleen from getting big. Generic imiglucerase injections are not yet available.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• high pressure in the blood vessels of the lungs (known as pulmonary hypertension)
• an unusual or allergic reaction to imiglucerase, other medicines, foods, dyes, or preservatives
• pregnant or are trying to get pregnant
• breast-feeding

How should I use this medicine?

Imiglucerase is for infusion into a vein. It is given in a hospital or health clinic setting by a trained health-care professional. Most people receive their medication at least once every 2 weeks. However, the dose for each person is adjusted just for them.

What if I miss a dose?

Try not to miss an appointment. Call your prescriber or health care professional for advice if you miss a dose.

What drug(s) may interact with imiglucerase?

There are no known interactions between imiglucerase and other medicines.

What should I watch for while taking imiglucerase?

Tell your prescriber or health care professional if imiglucerase does not improve your symptoms or if it makes your symptoms worse.

What side effects may I notice from receiving imiglucerase?

Side effects that you should report to your prescriber or health care professional as soon as possible:
During the infusion, let your prescriber know if any of the following occur:
• discomfort in the chest
• difficulty breathing or shortness of breath
• itching or skin rash
• feeling of dizziness or faintness
• palpitations or racing heartbeat

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
• backache
• diarrhea
• headache
• fever or chills
• nausea, vomiting
• stomach discomfort
• swelling, pain or itching at the injection site
• tired feeling

Where can I keep my medicine?

This medication is stored in the refrigerator, but since someone will give it to you, you will not have to store your doses at home.


Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

 
 
Wikipedia: imiglucerase
Imiglucerase
Systematic (IUPAC) name
Human Beta-glucocerebrosidase
Identifiers
CAS number 143003-46-7
ATC code A16AB02
PubChem  ?
DrugBank BTD00026
Chemical data
Formula C2532H3854N672O711S16 
Mol. mass 55597.4 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3.6-10.4 min
Excretion  ?
Therapeutic considerations
Licence data

EU US

Pregnancy cat.

?

Legal status
Routes  ?

Imiglucerase is a recombinant DNA produced analogue of human β-glucocerebrosidase. Cerezyme® is a freeze dried medicine containing imiglucerase, manufactured by Genzyme Corporation. It is given intravenously after reconstitution as a treatment for Type 1 Gaucher's disease.




 
 

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Copyrights:

Drug Info. Gold Standard. Copyright © 2008 by Gold Standard. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Imiglucerase" Read more

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