Not totally, but you can build up a tolerance to it.

Tolerance exists when the immune system does not respond to a particular antigen. All cells and tissues in the body contain antigens that normally do not stimulate an immune response. The immune system is said to exhibit tolerance toward such antigens.

It is a Pathological Condition in which the Immune System of human body fails, & the Immune cells cannot recognize the foreign Antigens (Microbes) or the neoplastic cells within the body leading to the Immune System Malfunctioning. Body responds nothing to the Allergens leading to severeness of the infection because the pathogenic infections are not halted or inhibited by Immune cells.
Immune tolerance or immunological tolerance is the process by which the immune system does not attack an antigen

Autoimmune

The correct statement about the prevention of immune attack on self is that the immune system has mechanisms in place, such as central and peripheral tolerance, to distinguish between self and non-self antigens. Central tolerance occurs during T and B cell development to eliminate self-reactive lymphocytes, while peripheral tolerance mechanisms like regulatory T cells help control any self-reactive immune responses that may develop later. Dysfunction in these tolerance mechanisms can lead to autoimmune diseases where the immune system attacks self antigens.