induration

1. The quality or condition of being hardened.
2. The act or process of becoming hardened.
3. Pathology. The hardening of a normally soft tissue or organ, especially the skin, because of inflammation, infiltration of a neoplasm, or an accumulation of blood.

In geology, the hardening of a rock, usually sedimentary, by drying, pressure, or cementation.

1. The hardening of a normally soft tissue or organ, especially the skin, because of inflammation, infiltration of a neoplasm, or an accumulation of blood.
2. A focus or region of abnormally hardened tissue.

The quality of being hard; the process of hardening; an abnormally hard spot or place.

• black i. — the hardening and pigmentation of the lung tissue, as in pneumonia.
• brown i. — 1. a deposit of altered blood pigment in the lung in pneumonia.
— 2. an increase of the pulmonary connective tissue and excessive pigmentation, due to chronic congestion from valvular heart disease, or to anthracosis.
• cyanotic i. — hardening of an organ from chronic venous congestion.
• granular i. — cirrhosis.
• gray i. — induration of lung tissue in or after pneumonia, without pigmentation.
• red i. — interstitial pneumonia in which the lung is red and congested.

The noun has one meaning:

Meaning #1: any pathological hardening or thickening of tissue
  Synonym: sclerosis