An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.

According to Biologists, the hyper polarization of a dendrite by a neurotransmitter is known as an inhibitory postsynaptic potential (IPSP).

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An EPSP is an excitatory postsynaptic potential, which represent input coming from excitatory cells, whereas an inhibitory postsynaptic potential represents input driven by inhibitory presynaptic cells.

It can be an excitatory postsynaptic potential (EPSP) or an inhibitory postsynaptic potential (IPSP), depending on the synapse. The EPSP depolarizes the membrane, while the IPSP hyperpolarizes it.