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international unit

 
Dictionary: international unit

n. (Abbr. IU)
  1. The quantity of a biologically active substance, such as a hormone or vitamin, required to produce a specific response.
  2. A unit of potency for similarly active substances, based on this quantity and accepted as an international standard.

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Britannica Concise Encyclopedia: international unit
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Any of several precision standards used in measuring physical quantities, such as mass, length, and time (see International System of Units), and also lighting systems, radiation processes, and pharmacology. The luminous intensity or candlepower of a light is expressed in candelas. The second is based on the frequency of radiation emitted by cesium-133 atoms. In radioactive decay, the international unit is the number of disintegrations per second in a sample. In pharmacology, the international unit is the quantity of a substance (vitamin, hormone, or toxin) that produces a specified effect when tested according to an internationally accepted procedure.

For more information on international unit, visit Britannica.com.

Food and Nutrition: international units
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iu

Used as a measure of comparative potency of natural substances, such as vitamins, before they were obtained in a sufficiently pure form to measure by weight. Still sometimes used (3.33 iu vitamin A = 1 μg; 40 iu vitamin D = 1 μg; 1 iu vitamin E = 1 mg).

Measures and Units: international unit
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electromagnetics (Metric) The units developed under the title electromagnetic units, forming the e.m.u. system, were adjusted by decimal multiplication to give the practical units, adopted at the first International Electrical Conference in 1881 as suitable for everyday electrical work. Accompanying explicit laboratory definitions of the ohm, ampere, and volt were established, making them base practical units instead of derived units as in the e.m.u., where these electrical units were defined in terms of mechanical equivalents. These new definitions were soon found to be discrepant with the intended and, despite some adjustments, are continuingly so (albeit by less than 0.05%). They were not even mutually self-consistent until the volt was made a derived unit, at the IEC of 1908, when the residual discrepancies were accepted via the use of the distinctive label ‘international ohm’, etc.

By Act of Congress in 1984, the USA created its own definitions of the ‘international units’, slightly different from the others, hence creating a set of US international units.

The true international units were in turn discarded at the end of 1947 in favour of new definitions within the metric m.k.s.A. system that became the SI system, these latest units often being called ‘absolute’, and generally agreeing with the original practical units rather than the ‘international’ ones. Typical values in SI terms are as follows:

1 international ampere= 0.999 85~ A
1 international coulomb= 0.999 85~ C
1 international farad= 0.999 510~F
1 international henry= 1.000 49~ H
1 international mho= 0.999 510~ S
1 international ohm= 1.000 49~ Ω
1 international volt= 1.000 34~ V

See international biological standards.

Sports Science and Medicine: International Unit
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IU

A unit used to measure the vitamin content of food, based on the vitamin's biological activity. Although IUs are still used, vitamin content is usually expressed as equivalent amounts of a pure standard form. For example, in the UK vitamin A content is given in microgrammes of pure retinal equivalent.

1. immunizing unit.
2. International Unit.

Wikipedia: International unit
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In pharmacology, the International Unit is a unit of measurement for the amount of a substance, based on measured biological activity or effect. "International Unit" is abbreviated as IU, or as UI from the French unité internationale, or as IE from the German Internationale Einheit.

The unit is used for vitamins, hormones, some medications, vaccines, blood products, and similar biologically active substances. Despite its name, the IU is not part of the International System of Units used in physics and chemistry.

Contents

Variance

The precise definition of one IU differs from substance to substance and is established by international agreement for each substance. There is no equivalence among different substances; for instance, one IU of vitamin E does not contain the same number of milligrams as one IU of vitamin A.

Equality

To define an IU of a substance, the Committee on Biological Standardization of the World Health Organization provides a reference preparation of the substance, arbitrarily sets the number of IUs contained in that preparation, and specifies a biological procedure to compare other preparations of that substance to the reference preparation. The goal in setting the standard is that different preparations with the same biological effect will contain the same number of IUs.

Equivalency

For some substances, the equivalent mass of one IU is later established. If that happens, the former IU definition for that substance is officially abandoned, in favor of a newly established weight. However, the unit count often remains in use nevertheless, because it is convenient. For example, vitamin E exists in a number of different forms, all having different biological activities. Rather than specifying the precise type and mass of vitamin E in a preparation, for the purposes of pharmacology it is sufficient, simply, to specify the number of IUs of vitamin E.

Mass equivalents of 1 IU

Difference from unit of enzyme activity

The IU should not be confused with the enzyme unit, also known as the International unit of enzyme activity and abbreviated as U.

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Copyrights:

Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.  Read more
Britannica Concise Encyclopedia. Britannica Concise Encyclopedia. © 2006 Encyclopædia Britannica, Inc. All rights reserved.  Read more
Food and Nutrition. A Dictionary of Food and Nutrition. Copyright © 1995, 2003, 2005 by A. E. Bender and D. A. Bender. All rights reserved.  Read more
Measures and Units. A Dictionary of Weights, Measures, and Units. Copyright © Donald Fenna 2002, 2004. All rights reserved.  Read more
Sports Science and Medicine. The Oxford Dictionary of Sports Science & Medicine. Copyright © Michael Kent 1998, 2006, 2007. All rights reserved.  Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "International unit" Read more