An isothermal calorimeter is a tool used to bind small molecules to larger macromolecules, and determine the thermodynamic parameters of interactions in a solution. An isoperibol calorimeter measures the heat created by a sample burned under an oxygen atmosphere in a closed vessel surrounded by water, in controlled conditions. The measurement is known as a BTU value.

A calorimeter is a device used for calorimetry, the science of measuring the heat of chemical reactions or physical changes as well as heat capacity. The word calorimeter is derived from the Latin word calore, meaning heat. Differential scanning calorimeters, isothermal microcalorimeters, titration calorimeters and accelerated rate calorimeters are among the most common types. A simple calorimeter just consists of a thermometer attached to a metal container full of water suspended above a combustion chamber.

quenching means (the act of extinguishing; causing to stop burning) "the extinction of the lights"

Isothermal crystallization done with respect to time and non isothermal with respect to temperature

isothermal means 'constant temperature'

so to be non-isothermal means to have non-constant temperature.