At one time scientists thought it came from comets, but now that we've learned more about the relative isotopic abundances in comets, that is no longer seeming quite so likely.
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Separation of a mixture according its isotopic composition.
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explain the mechanism of diffusion in the separation of isotopic mixtures
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It is approximately equivalent to the number of protons and
neutrons in the atom (the mass number) or to the average number
allowing for the relative abundances of different isotopes.