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John Robert Vane

 
 
Columbia Encyclopedia: Sir John Robert Vane
Vane, Sir John Robert, 1927–2004, British pharmacologist, Ph.D. Oxford, 1953. With B. I. Samuelsson and Sune K. Bergström, Vane was awarded the 1982 Nobel Prize in Physiology or Medicine. The trio won the prize for their identification and description of various compounds known as prostaglandins, which affect such functions as blood pressure and body temperature. Vane's work helped explain the effects on the body of aspirin, the world's most widely used drug and also contributed to the discovery and development of cox-1 and cox-2 inhibitors (see nonsteroidal anti-inflammatory drug). He was knighted in 1984.
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(vān), John Robert Born 1927.

British pharmacologist. He shared a 1982 Nobel Prize for research on prostaglandins.

 
Wikipedia: John Robert Vane
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John Robert Vane
Born 29 March 1927
Tardebigg, Worcestershire
Died 19 November 2004
Kent
Citizenship British
Nationality English
Fields pharmacology
Known for aspirin, prostaglandin
Notable awards Nobel Prize in Physiology or Medicine in 1982

Sir John Robert Vane (29 March 1927 – 19 November 2004) was an English pharmacologist, born in Tardebigg, Worcestershire. His father was the son of immigrants from Russia and his mother came from a Worcestershire farming family. He was educated at King Edward's School in Edgbaston, Birmingham, and studied Chemistry at the University of Birmingham in 1944. Vane completed a doctorate in pharmacology from the University of Oxford in 1953.

He held a post at the Institute of Basic Medical Sciences of the University of London in the Royal College of Surgeons of England for 18 years. During that time he developed certain bioassay techniques that led to important scientific discoveries. He won a Nobel Prize in Physiology or Medicine in 1982 for his work on aspirin in which he discovered it inhibited prostaglandin biosynthesis[1][2][3][4].

In 1973, Vane left academia and took up the position of director of research of the Wellcome Foundation. He was knighted in 1984. In 1985 he returned to academic life at the William Harvey Research Institute at the Medical College of St Bartholomew's Hospital (now Barts and The London, Queen Mary's School of Medicine and Dentistry).[5].

He died on November, 19, 2004 in Princess Royal Hospital, Kent from long-term complications arising from leg and hip fractures he sustained in May of that year.

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Copyrights:

Columbia Encyclopedia. The Columbia Electronic Encyclopedia, Sixth Edition Copyright © 2003, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/  Read more
Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "John Robert Vane" Read more