Males with Lesch-Nyhan syndrome develop neurologic problems during infancy. Infants with Lesch-Nyhan syndrome have weak muscle tone (hypotonia) and are unable to develop normally.

Lesch-Nyhan syndrome was first described in 1964 by Drs. Michael Lesch and William Nyhan. The enzyme deficiency that causes the disorder was discovered in 1967 by a researcher named Seegmiller.

males

Lesch-Nyhan syndrome is a rare genetic disorder that affects males. Males with this syndrome develop physical handicaps, mental retardation , and kidney problems.

He was one of the men who discovered and researched the Lesch-Nyhan Syndrome. The Lesch-Nyhan syndrome is a syndrome inherited as a sex-linked recessive disorder. This syndrome causes you to bite your lips and fingers. So basically it causes you to start biting yourself.